1. Formative
Test

2. Q1- Anti-lipid drug that usually causes cutaneous vasodilation after each dose when the drug is started
A- gemfibrozil     
B- niacin     
c- cholestyramine
d-  clofibrate   
e-  lovastatin

3. A- clofibrate B- gemfibrozil C- cholestyramine D- pravastatin
Q2- Antilipidemic drug most likely to reduce serum digoxin levels:
A- clofibrate  
B- gemfibrozil
C- cholestyramine
D- pravastatin
E- niacin

4. Q3- 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of:-
(A) Agranulocytosis
(B) Gallstones
(C) Lactic acidosis
(D) Myopathy
(E) Thyrotoxicosis

5. Q4-A 35year- old male with markedly elevated plasma triglycerides and LDL levels is treated with gemfibrozil. What is the mechanism of action of gemfibrozil?
Sequestration of bile acids
Decreased hepatic secretion of VLDL
Increased lipoprotein lipase activity
Inhibition of HMG-CoA reductase
Decreased oxidation of plasma lipids

6. Q5-Which of the following drugs recommended for the lowering of blood cholesterol inhibits the synthesis by blocking 3-hydroxy-3-methylglutaryl coenzyme A reductase?
Gemfibrozil
Niacin
Ezetimibe
Atorvastatin
Cholestyramine