1. ReDVA Meeting Barcelona Wednesday 15th April 2015 WP 1: Research Supervision & Management

2. Benefits to Each Institution
Limerick Objective: Computational fluid dynamics analysis through ReDVA
Benefits:
Acquisition of 3D MRI NHV and patient data
Imaging research
Contrast media
MRI expertise
Pulse sequences
Protocol design
US expertise
Identification of different fistula models
- elastography
CFD research in relation to VA – hardware & software
Industrial Collaboration
Medical devices
Flow rig

3. Benefits to Each Institution
Guerbet Objective: Development of new methods of assessment of ReDVA using imaging techniques
Benefits:
Expertise in:
imaging
vascular access surgery
medical devices
Clinical imaging research in relation to VA
Development & validation of imaging techniques
Data mining and development of imaging techniques
– contrast usage in ReDVA population

4. Benefits to Each Institution
Birmingham Objective: Clinical data mining of ReDVA patient events
Benefits:
Imaging contrast media research and usage
Data mining & development of techniques
Research into clinical imaging of VA
Development of imaging techniques
Medical device research

5. Benefits to Each Institution
Vascular Flow Technologies Objectives: To outline the surgical strategies and optimisation of VA devices to improve long-term VA patency; To develop business planning opportunities for commercial partners
Benefits:
Expertise in clinical imaging and clinical research
Flow rig analysis
CFD research – vascular hemodynamics
Medical device research

6. Benefits to Each Institution
Dundee Objectives: Definition, supervision & reporting of research activities: Flow rig simulations of ReDVA models
Benefits
Medical device research
Imaging research & strategies for ReDVA
CFD research - hemodynamics
Clinical research VA surgery
Contrast media research & education

7. Milestones Milestone Name/Comment Month M1.1
Project website – Complete M3
M2.1
Clinical data mining & analysis - Complete
M12
M5.1
Imaging data collection – Not Complete
Dundee struggling to recruit
M18
M3.1
Validation of US/MRI techniques
Guerbet Milestone – Conor/Katarina?
M24
M1.2
Fellow career development plans
Circulated before fellows leave
M30

8. Deliverables Deliverable Centre Description of work Deadline D6.1 UD
Serum Analysis
M12: Completed
D2.1
QEHB
Data collection & archiving
Imaging - regulations? Dundee
M18:Completed
D3.1 GU
Standardisation of US/MRI techniques across ReDVA centres. RR/LB designed protocol
M18: Completed
D4.1
UD/UL
Identification of different fistula models. This work to be linked to flow rig
D5.1 UL
Acquisition of patient 3D MRI data
Dundee struggling to recruit patients
M18: Incomplete
D3.2
Validation of imaging techniques across ReDVA centres (MRI,US)
M24: Conor?
D5.2
Construction of safety meshes
M24
D4.2
Flow rig report: Time!
M36:
D5.3
Inlet Criteria: Time!
M36

9. Dissemination Project going to plan –
Meeting most milestones & deliverables
Many successes linked to our work
Thinking ahead – milestones and deliverables
Focus on
Recruitment/Secondment
Patient Recruitment

10. Knowledge Transfer/Training
Opportunities available to UD, UL, & VFT Secondees
Interventional Radiology Course
Session with Vascular Surgeon
Designing an MRI Protocol
MR Imaging Techniques – Pulse Sequences
Supercomputing Overview
Flow Rig Simulations
Ultrasound Techniques including Elastography
Developing a Pre-Clinical Model
CAD Stent Design
All secondees are encourage to attend course/conferences/meetings

11. Knowledge Transfer/Training
Opportunities Open to QEHB & GU Secondees
Cochrane training modules on systematic reviews and meta-analysis of diagnostic test accuracy studies (University of Amsterdam and University of Birmingham).
Cochrane author training module for diagnostic test accuracy systematic reviews (university of Birmingham)
Seminar and meeting with European Renal Association regarding guidelines group and data extraction from scientific literature.
Guerbet introductory program. 
Medical and regulatory affairs training- provided by Guerbet and Dr E Lancelot. 
Theory of MRI and contrast agents-provided by Guerbet, Dr JS Raynaud.

12. Events Attended Event/Date Poster Presentation (n)
Oral Presentation (n)
British Renal Week 2014
VASA 2014
VASBi 2014
Yes
ASN 2014
Yes (3)
WCN 2015
Yes (1)
VAS 2015
Yes (9)
Yes (2)

13. Publications
During and after the project, the coordinator shall provide reference of all scientific publications relating to foreground at the latest two months following the publication.
All publications shall include the following statement to indicate that said foreground was generated with the assistance of financial support from the European Union:
“The research leading to these results has received funding from the European Union’s Seventh Framework Programme (FP7/ ) under grant agreement no ”
Only publications that acknowledge ReDVA can be included in our publications list!
Dundee -
QEHB – 7 publications drafted, in press, submitted or requiring minor revisions GU
UL -
VFT -

14. Collaborations & Proposals
Centre
Collaboration or Proposal
VFT
Potential collaboration commercial partners in Europe & USA
QEHB
Collaboration with vascular surgeons in Paris
UD/QEHB
Nationwide data mining – multi centre collaboration
ERBP collaboration - review of vascular access guidelines
QEHB/UD
EuroDOPPS proposal – assessing data
QEHB/UD/GU
Cochrane Review

15. Questionnaires & Newsletter/Outreach
Centre
QEHB
Multi-centre questionnaire based study to define imaging practice in UK and EU centres UD
Patient focused questionnaire to create patient timeline from vascular access creation onwards – success/failure
Quarterly newsletter - outreach
Project website

16. Commitment to Outreach

17. IPR

18. Mid Term Meeting Report
Submission date: On or before
Cover significant outcomes of the work performed
research & training
methodologies, scientific results,
networking and opening up career opportunities to Marie Curie Research Fellows.
Publications & Presentations
Should cover the period from the beginning of the project

19. What I need For Mid-Term Review Report
Agreement to milestone & deliverable changes
Work performed since start of project
Highlights – potential impact
List of all publications that have acknowledge ReDVA
Conference attendances/presentations linked to ReDVA
Training opportunities offered to secondees
Knowledge exchange
A Paragraph detailing your use of resources – VFT/UL
Financial statement from each beneficiary
Collaborations
Outreach work

20. Secondee Questionnaire
At least two weeks before the mid-term review meeting all recruited researchers employed in the frame of the project must complete and submit the on-line Mid-Term Assessment questionnaire
Questionnaires can be found at:
Information in questionnaire will be treated confidentially and will mainly be used to assess the satisfaction of fellows and the overall impact of the action.
Questionnaires should also be used as an opportunity to make suggestions on how to improve the training opportunities in the network.