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Fig. 1 Top, Locomotor activity in male bGH transgenic mice (n = 10) and nontransgenic control mice (n = 25) at their first encounter with the locomotor.

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Presentation on theme: "Fig. 1 Top, Locomotor activity in male bGH transgenic mice (n = 10) and nontransgenic control mice (n = 25) at their first encounter with the locomotor."— Presentation transcript:

1 Fig. 1 Top, Locomotor activity in male bGH transgenic mice (n = 10) and nontransgenic control mice (n = 25) at their first encounter with the locomotor activity boxes. Statistics were determined by two-factor repeated measures ANOVA: group effect, P = ; time effect, P < ; and interaction term, P < Bottom, Locomotor activity in bGH transgenic mice (n = 10) and nontransgenic control mice (n = 25) at their second encounter with the locomotor activity boxes. All animals received 0.9% NaCl, ip, 5 min before placement in the boxes. Statistics were determined by two-factor repeated measures ANOVA: group effect, P = ; time effect, P < ; and interaction term, P = Bovine Growth Hormone Transgenic Mice Display Alterations in Locomotor Activity and Brain Monoamine Neurochemistry1 Endocrinology. 1999;140(12): doi: /endo Endocrinology | Copyright © 1999 by The Endocrine Society

2 Fig. 2 Locomotor activity in bGH transgenic mice (n= 9) and nontransgenic control mice (n = 25) at their third encounter with the locomotor activity boxes. Left panel, All animals received 1 mg/kg d-amphetamine, ip, 5 min before placement in the boxes. Statistics were determined by two-factor repeated measures ANOVA: group effect, P = ; time effect, P < ; and interaction term, P = Right panel, The calculated difference between the locomotor activity induced by d-amphetamine week 3 and that induced by 0.9% NaCl week 2 in each animal and group. Statistics were determined by two-factor repeated measures ANOVA: group effect, P = ; time effect, P < ; and interaction term, P = Bovine Growth Hormone Transgenic Mice Display Alterations in Locomotor Activity and Brain Monoamine Neurochemistry1 Endocrinology. 1999;140(12): doi: /endo Endocrinology | Copyright © 1999 by The Endocrine Society

3 Fig. 3 Locomotor activity in bGH transgenic mice (n= 10) and nontransgenic control mice (n = 23) at their fourth encounter with the locomotor activity boxes. Left panel, All animals received 2.5 g/kg ethanol, ip, 5 min before placement in the boxes. Statistics were determined by two-factor repeated measures ANOVA: group effect, P = ; time effect, P < ; and interaction term, P = Right panel, The calculated difference between the locomotor activity induced by ethanol week 4 and that induced by 0.9% NaCl week 2 in each animal and group. Statistics were determined by two-factor repeated measures ANOVA: group effect, P = ; time effect, P = ; and interaction term, P = Bovine Growth Hormone Transgenic Mice Display Alterations in Locomotor Activity and Brain Monoamine Neurochemistry1 Endocrinology. 1999;140(12): doi: /endo Endocrinology | Copyright © 1999 by The Endocrine Society

4 Fig. 4 Tissue levels of monoamines and monoamine metabolites, and quotients between metabolites and monoamines, in bGH transgenic mice and nontransgenic control mice in seven different brain regions. Data are expressed as a percentage of the control value. Shown are the mean ± sem of n observations. Statistics were determined by Student’s t test: *, P < 0.05; **, P < 0.01; and*** , P < Bovine Growth Hormone Transgenic Mice Display Alterations in Locomotor Activity and Brain Monoamine Neurochemistry1 Endocrinology. 1999;140(12): doi: /endo Endocrinology | Copyright © 1999 by The Endocrine Society

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