1. Research Challenges and Experiences
Esmita Charani
NIHR Health Protection Research Unit in HCAI and AMR

2. Background MPharm 2002 – not all that exciting
Trained at Cambridge University Hospitals
MSc 2006 – pivotal
No research experience
Imperial 2009 – 3 year fixed term contract
PhD Imperial 2017

3. Challenges Independent working Looking out for funding Rejection
NHS – Academia interface
Ethics
Bureaucracy

4. Challenges Independent working Looking out for funding Rejection
NHS – Academia interface
Ethics
Bureaucracy
You are not re-inventing the wheel – someone has done it before you

5. Experiences Wealth of knowledge Gaining expertise
Exposure to leaders in the field
Travel
Networking
Influencing decision making
What motivates your work?
Insight

6. Research highlights External collaborations &
national and international reports and policy
Research led by the Centre for Infection Prevention and Management &
NIHR HPRU in HCAI and AMR
2008
MSc in Infection Management at Imperial
2009
2010
Antibiotic Stewardship programmes – what’s missing. J Antimicrob Chemother Nov;65(11):
2011
Considering nurse’s role in antimicrobial stewardship. J Infect Prev Jan; 12(1):6-10.
Behaviour Change Strategies to Influence Antimicrobial Prescribing – Systematic Review Clin Infect Dis Oct;53(7):
2012
Optimisation of IP&C by use of behaviour change – a systematic review. Lancet Infect Dis Apr;12(4):
Health technology assessment report. Department of Health. Development and Implementation of a smartphone app in AMS.
When the user is not the chooser: learning from stakeholder involvement in technology adoption decisions in IP&C. J Hosp Infect Jul;81(3):163-8.
2013
Understanding determinants of antimicrobial prescribing within hospitals: the role of prescribing etiquette.
Clin Infect Dis Jul;57(2):
Antimicrobial stewardship programmes: the need for wider engagement. BMJ Qual Saf Nov;22(11):885-7.
UK 5 year Antimicrobial Resistance Plan Strategy 2013 – 2018, Department of Health
Analysis of the development and implementation of a smartphone application for delivery of antimicrobial policy.
J Antimicrob Chemother Apr; 68(4):960-7.
2014
WHO AMR – Global report on surveillance
Fragmentation of care in peripheral vascular catheter care. PLoS One Jan 14;9(1): e86167.
The role of behaviour change in AMS. Infect Dis Clin North Am Jun;28(2):
UK Commons Select Committee report on AMR
Do smartphone applications in healthcare require governance? BMC Med Feb 14;12:29. .
2015
Health Foundation Report: Infection prevention and control : lessons from acute care in England.
Lancet series on AMR: Understanding the mechanisms and drivers of antimicrobial resistance. Lancet Jan;387(10014):
Lack of weight recording in patients being administered narrow therapeutic index antibiotics. BMJ Open. Apr 2;5(4):e
Collaboration with Norway: An antimicrobial stewardship programme. Antimicrob Resis Infect Control Jun 4;4:24.
Towards changing healthcare worker behaviours in IP&C. J Hosp Infect Jun;90(2):
Improving the design and reporting of behaviour change interventions in AMS. Int J Antimicrob Agents Mar;45(3):
PHE Publication: Literature review of behaviour change and antibiotic prescribing in healthcare settings
Antimicrobial dosing in obesity. J Antimicrob Chemother Oct;70(10):
2016
AMS: are we failing in cross-specialty clinical engagement? J Antimicrob Chemother Feb;71(2):554-9.
A needs assessment study for optimising prescribing practice in secondary care junior doctors. BMC Infect Dis Aug 30; 16(1):456.
Review on AMR O’Neill Report
Mapping AMS in undergraduate medical, dental, pharmacy, nursing and veterinary education. PLoS One 2016 Feb29;11(2):e
Preventing bloodstream infection in children. What’s the CATCH? Lancet Jul 30;388(10043):462-3.
Promoting medical student engagement with AMS through involvement in undergraduate research. J Infect Sep 9. pii:SO (16)
ESRC call for social science research into AMR
What are factors driving antimicrobial resistance? Perspectives from a public event in London. BMC Infect Dis Sep 2;16:465.
Serious electronic games as behaviour change interventions. Antimicrob Resist Infect Control Oct 12;5:34.
General Assembly of the United Nations High-Level meeting on AMR
Patient engagement with infection management in secondary care. BMJ Open Oct 31;6(10):e
Coverage of AMS across UK Postgraduate training curricula. J Antimicrob Chemother Nov;71(11):
Information provision for antibacterial dosing in the obese patient. J Antimicrob Chemother Dec; 71(12):
Mapping decision pathways of acute infection. BMC Med Dec 12;14(1):208.
2017
Cochrane systematic review on behaviour change interventions in AMS – due for publication in 2017
The effect of adding a mobile health intervention to a multimodal AMS programme – an interrupted time series study.
In press, J Antimicrob Chemother.
PHE Publication: embedding national antimicrobial prescribing and stewardship competences into curricula
2018

9. Nursing summit at Imperial 2017

10. Great Team Work