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Nervous system: brain, spinal cord

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Presentation on theme: "Nervous system: brain, spinal cord"— Presentation transcript:

1 Nervous system: brain, spinal cord
Dr. L. Kiss Anna Department of Human Morphology and Developmental Biology, Semmelweis University 2015

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5 MACROSCOPY Enlargements: Cervical enlargement (C4-T1)
Lumbosacral enlargement (L2-S3) Conus terminalis Cauda equina Filum terminale Central nervous system Brain Spinal cord Peripheral nervous system Nerves Ganglia

6 cauda equina

7 Lumbal punction

8 MENINGES Dura mater Arachnoid Pia mater: Denticulate ligament

9 Meningeal layers of the spinal cord
ganglion spinale arachnoidea fila radicularia dorsalia dura mater ligamentum denticulatum

10 Meningeal layers Dura mater: outer layer: endorachis inner layer
Arachnoid layer Pia mater Epidural spce Subdural space Subarachnoid space

11 MENINGES Epidural space Subarachnoid space Denticulate ligament

12 Blodd supply of the spinal cord
radicular arteries vertebral artery subclavian artery radicular arteries Aortic arch pathway of the vertebral artery

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14 Vasocorona medullaris
Vertebral artery: a.spinalis anterior a spinalis posterior Radicular arteries: cervical: vertebral a. ascending. cerv. a. deep cerv. a. thoracal: intercostal aa. lumbal: lumbal aa. sacral: lateral sacr. art.

15 CROSS SECTION Dorsal median sulcus Gray matter White matter
Ventral median fissure Central canal

16 Cross section of the spinal cord
post. (dors.) median sulcus post. (dorsalis)horn intermediate zone (Th and L2-L3): lat. horn central canal ant. (ventral) horn ant. (ventr.) median fissure

17 SPINAL CORD SEGMENT

18 SPINAL NERVES Dorsal branch Ventral branch

19 SPINAL CORD SEGMENTS Spinal cord ends at the level of the L1 vertebra in adults Lumbar and sacral roots travel several vertebrae down: cauda equina

20 SPINAL NERVES

21 SPINAL CORD SEGMENTS Number of segments: 8 cervical (!) 12 thoracic 5 lumbar 5 sacral 1 coccygeal

22 SEGMENTAL INNERVATION
Dermatomes: segmental symptomes

23 CERVICAL PLEXUS AND BRACHIAL PLEXUS
Cervical plexus (C1-4): Lesser occipital nerve Greater auricular nerve Transverse nerve of the neck Supraclavicular nerves Ansa cervicalis Phrenic nerve Branchial plexus (C5-T1): Superior trunk (C5-6) Middle trunk (C7) Inferior trunk (C8-T1)

24 CERVICAL PLEXUS AND BRACHIAL PLEXUS
Branchial plexus (C5-T1): Lateral cord (C5-7) Lateral pectoral nerve Musculocutaneus nerve Median nerve (lateral root) Medial cord (C8-T1) Medial pectoral nerve Medial cutaneous n. of arm Medial cutaneous n. of forearm Ulnar nerve Median nerve (medial root) Posterior cord (C5-T1) Subscapular nerves Thoracodorsal nerve Axillary nerve Radial nerve

25 LUMBOSACRAL PLEXUS Lumbar plexus (T12-L4): Iliohypogastric nerve
Ilioinguinal nerve Genitofemoral nerve Lateral cutaneous nerve of thigh Obturator nerve Femoral nerve Sacral plexus (L4-S3): Muscular branches Superior gluteal nerve Inferior gluteal nerve Posterior cutaneous nerve of thigh Sciatic nerve Tibial nerve Common peroneal nerve Pudendal nerve

26 Brain

27 Brain Brain stem Medulla oblongata Pons Midbrain (mesencephalon)
Cerebellum Diencephalon (thalamus, hypothalamus, hypophysis) Cerebrum Brain stem

28 MEDIANSAGITTAL SECTION
OF THE BRAIN STEM M M Mo P Mo

29 Meningeal layers of the brain
Dura mater: falx cerebri, tentorium cerebelli, falx cerebelli sinuses: venous blood Aracnhoir layer: cisterns CSF Pia mater: blood vessels

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31 VENTRICLES Lateral ventricle 3rd ventricle 4th ventricle

32 CEREBROSPINAL FLUID Production: choroid plexus: into ventricles
Absorption: arachnoid villi: from subarachnoid space into superior sagittal sinus

33 BRAIN: Cerebrum SUPERIOR VIEW
Frontal lobe Longitudinal cerebral fissure Parietal lobe Occipital lobe

34 BRAIN: MEDIANSAGITTAL CUT
Longitudinal cerebral fissure Parietal lobe Corpus callosum Occipital lobe Frontal lobe Transverse cerebral fissure Temporal lobe Cerebellum

35 BRAIN: LATERAL VIEW Parietal lobe Central sulcus Frontal lobe
Occipital lobe Transverse cerebral fissure Lateral cerebral sulcus Cerebellum Temporal lobe Pons Medulla oblongata

36 praecentral gyrus central sulcus postcentral gyrus

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38 3rd and 5th layers-pyramidal cells

39 BRAIN: INFERIOR VIEW Longitudinal cerebral fissure Frontal lobe
Olfactory nerve (I) Optic nerve (II) Optic chiasm Temporal lobe Optic tract Diencephalon Pons Medulla oblongata Cerebellum Occipital lobe

40 BLOOD SUPPLY: ARTERIES
Arterial supply: Vertebral artery Internal carotid artery internal carotid artery vertebral artery

41 CIRCLE OF WILLIS Anterior communicating a. Anterior cerebral a.
Internal carotid a. Middle cerebral a. Posterior communicating a. Posterior cerebral a. Basilar a. Vertebral a.

42 BLOOD SUPPLY: VEINS Venous drainage: Internal jugular vein: Sinuses
Cerebral veins

43 BRAIN STEM: MEDULLA Glossopharyngeal n. (IX) Vagus n. (X) Olive
Accessory n. (XI) Pyramid Hypoglossal n. (XII)

44 Midbrain (cross section)
tectum: sup and inf colliculi Crus cerebri

45 BRAIN STEM Cerebral aqueduct Cerebellum Midbrain Pons Fourth ventricle
Medulla Central canal

46 CEREBELLUM Cerebellar hemisphere Vermis Tonsil

47 CEREBELLUM Fastigial nucleus Cerebellar cortex Globose nucleus
Emboliform nucleus White matter Dentate nucleus

48 CEREBELLUM Superior cerebellar peduncle Middle cerebellar peduncle
Inferior cerebellar peduncle

49 Functional division of the nervous system
Somatic Autonomic voluntary - unvoluntary starts and stops functions - regulates the functions (slow down-speed up) segmental - network sympathetic parasympathetic thora-columbar cranio-sacral

50 Autonomic nervous system: efferent part
Sympathetic Parasympathetic - speeds up the functions - slows down the functions (except for digestive system) (except for the digestive system) - empties the stores - filles in the stores - adrenalin, noradrenalin - acetylcholine (sympatho-adrenal system) - last longer - shorter effect general effect - local effect short praeganglionic fibers -longer praeganglionic fibers longer postganglionic fibers shorter postganglionic fibers

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52 Dr. Nándor Nagy picture

53 References Lecture and pictures of Dr. Nandor Nagy Sobotta atlas
Wikipaedia


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