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Volume 115, Issue 5, Pages (November 1998)

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Presentation on theme: "Volume 115, Issue 5, Pages (November 1998)"— Presentation transcript:

1 Volume 115, Issue 5, Pages 1072-1078 (November 1998)
Long-term treatment of ulcerative colitis with ciprofloxacin: A prospective, double-blind, placebo-controlled study  Ulla M. Turunen, Martti A. Färkkilä, Kalle Hakala, Kari Seppälä, Aulikki Sivonen, Mats Ögren, Matti Vuoristo, Ville V. Valtonen, Tatu A. Miettinen  Gastroenterology  Volume 115, Issue 5, Pages (November 1998) DOI: /S (98) Copyright © 1998 American Gastroenterological Association Terms and Conditions

2 Fig. 1 Life-table analysis of occurrence of treatment failures in patients treated with ciprofloxacin (—; 38 patients) or placebo (- - -; 45 patients) in addition to conventional treatment with steroids and mesalamine. Steroids were started with 0.75 mg/kg, reduced to 0.25 mg/kg at monthly intervals, and tapered off after 3 months. Ciprofloxacin or placebo was administered for 6 months, and mesalamine was administered throughout the 12 months (open arrow, control visit; closed arrow, colonoscopy). Gastroenterology  , DOI: ( /S (98) ) Copyright © 1998 American Gastroenterological Association Terms and Conditions

3 Fig. 2 Life-table analysis of occurrence of treatment failures in patients treated with peroral steroids before study entry and subsequently treated with ciprofloxacin (—; 17 patients) or placebo (- - -; 26 patients), as well as with the study regimen of steroids and mesalamine. Gastroenterology  , DOI: ( /S (98) ) Copyright © 1998 American Gastroenterological Association Terms and Conditions


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