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Stem cells in the embryonic kidney

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Presentation on theme: "Stem cells in the embryonic kidney"— Presentation transcript:

1 Stem cells in the embryonic kidney
R. Nishinakamura  Kidney International  Volume 73, Issue 8, Pages (April 2008) DOI: /sj.ki Copyright © 2008 International Society of Nephrology Terms and Conditions

2 Figure 1 Metanephric mesenchymal progenitors. (a) In vitro colony formation from the metanephric mesenchyme on feeder cells expressing Wnt4. (b) Only Sall1-GFPhigh cells (upper panels) differentiated into kidney structures in organ culture, whereas Sall1-GFPlow cells (lower) disappeared. (c) Hematoxylin–eosin staining of sections of Sall1-GFPhigh aggregates at day 10. Tubule- (t) and glomerulus-like structures (g) are seen. Bars: (a) 50, (b) 500, (c) 25 μm. Kidney International  , DOI: ( /sj.ki ) Copyright © 2008 International Society of Nephrology Terms and Conditions

3 Figure 2 Kidney development in view of stem cell biology. See the text for details. MET, mesenchymal-to-epithelial transition. Kidney International  , DOI: ( /sj.ki ) Copyright © 2008 International Society of Nephrology Terms and Conditions


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