1. Making life possible since 3,499,997,985 B.C.
Enzymes
Making life possible since 3,499,997,985 B.C.

2. Enzymes Biological catalysts Increases speed of reactions
Example: digesting food or breaking down glucose
Not changed during reactions
Can be used over and over
Enzyme: rocketase

3. Enzyme Functions Active site Breaks molecules in half OR
Builds molecules
Active site
Spot where molecules bind and react
Specific shape for specific things

4. Substrate The material enzymes bond with
MUST match the shape of the enzymes active site
Like a key matches only one lock
A substrate only matches one enzyme

5. Complex When enzymes and substrates fit together
AKA enzyme/substrate complex

6. Check Your Understanding CYU
What reaction did this enzyme do to this substrate? (break or build)

7. Activation energy Energy needed to start reactions Example fire
Do logs light on fire randomly? No they require a spark AKA “activation energy”
Will rocks fall randomly?
Needs a push
Activation NRG

8. Enzymes and activation NRG
Enzymes lower NRG needed to start a reaction
Speeds up RXN by lowering activation NRG
Ex: food breaks down on its own (molding ect) but it takes a LONG time. You eat food and it breaks down quickly, enzymes lower NRG needed to break food down

9. Factors that affect enzymes
Temperature
Too hot proteins fall apart (denature)
Causes a change in the shape of the active site
Too cold (frozen) proteins never meet up with substrates
Acidity or (pH)
Too much acid proteins fall apart (denature)
Too little acid proteins and substrates don’t “stick” or bond together.

10. CYU
If a protein changes shape due to the temperature getting way too hot, will it still be able to bind with its substrate? Why or why not?

11. CYU
What are two factors that affect an enzymes ability to do their job?
Temperature
Acid or base (pH)

12. CYU
Why is it so important your body needs to maintain homeostasis-relate it to enzymes.
Temperature
Acid or base (pH)

13. Enzyme Movie

14. Exit/Entrance slip Summarize the relationship between an enzyme and a substrate.