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What do all these have in common?
ants rattlesnake termites sea urchin turtle cow cod pigs feet monkey brains squid sheep eyeballs snails octopus seaweed worms
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Food Food – contains nutrients
Nutrients are substances in foods that the human body can digest, absorb, and use for its metabolism.
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Roughage (also called fiber) is indigestible material in foods.
Humans are heterotrophic and therefore, must ingest food. Food includes nutrients and roughage (fiber). Roughage (also called fiber) is indigestible material in foods.
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carbohydrates, proteins, lipids, minerals, vitamins, and water.
Nutrients carbohydrates, proteins, lipids, minerals, vitamins, and water.
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III‑1. Human Nutrition Nutrition includes those activities by which organisms obtain and process nutrients needed for energy, growth, repair and regulation.
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Carbohydrates, lipids, and proteins require digestion.
Vitamins, minerals, and water are small molecules and can be absorbed without digestion. Carbohydrates, lipids, and proteins require digestion.
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Nutritional requirements vary with an individual's age, sex and activities.
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How does food become feces?
food feces
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Digestion - the process of breaking food down into a smaller, simpler form, so it can be used by the cell(s) of an organism
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Place these in order from smallest to largest (from simple to most complex)
Organ systems Cells Tissues Organs
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Cells Tissues Organs Organ systems Simple Complex
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Levels of Organization in the Human Body
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Salivary glands epiglottis mouth esophagus tongue liver stomach pancreas Small intestine Large intestine appendix anus rectum
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liver stomach pancreas Gall bladder
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The human digestive system consists of a continuous "one‑way" tube and the assisting accessory organs.
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How is food processed in the mouth?
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Oral Cavity
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1. Oral Cavity (mouth) Ingestion of food occurs through the mouth (oral) cavity which contains the teeth, tongue, and the openings from the salivary glands.
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canines incisors rip, grip, tear food cut (bite) food
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incisors canines premolars molars
grind, crush food crush food
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What is the function of the teeth?
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The teeth function in the mechanical breakdown of food which serves to increase the surface area of the food for enzyme action.
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plaque
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What are the functions of the tongue?
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Functions of the Tongue
pushes food around mouth and between teeth mixes food with saliva tastes the food - mmmm!
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Functions of the Tongue
forms mass of food for swallowing pushes food to the back of throat (pharynx) for swallowing
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What are those bumps on her tongue?
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What is the tongue made of?
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Tongue composed of skeletal muscle with an outer layer of mucous membrane
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Taste Zones Bitter Sour Salt Sweet
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WRONG!
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Salivary Glands
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The chemical digestion of carbohydrates begins here.
The salivary glands secrete saliva which contains the enzyme amylase which digests starch into disaccharides.
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Functions of Saliva lubricates food contains lysozyme contains salivary amylase
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This happens later on! (Not in the mouth)
disaccharide monosaccharide
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Composition of Saliva 95% water mucus salivary amylase lysozyme
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uvula ?
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Swallowing animation http://www.youtube.com/watch?v=Yg_kAqBlp9Y
Good for review of entire dig. system
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How does food get to the stomach even if you’re upside down?
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Peristalsis The wavelike muscular contractions that push food through the digestive tube
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Peristalsis http://www.youtube.com/watch?v=YH3U_SLp9G0&feature=related
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How is the action of peristalsis like surfing a wave?
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Peristalsis
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Endoscope
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CHEW BEFORE YOU SWALLOW!
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As a result of swallowing, food moves into the esophagus.
This begins the peristaltic action of the esophagus which moves the food to the stomach and through the GI tract.
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(left) and stomach lining (right)
Normal esophagus (left) and stomach lining (right) Esophageal cancer (stomach lining on left)
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stomach
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Inside the Stomach
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1. Stomach The stomach is a muscular organ in which food is temporarily stored, liquefied to chyme, and where protein digestion begins. Its lining contains gastric glands which secrete enzymes and hydrochloric acid.
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Stomach muscular organ stores food mechanical digestion
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Stomach chemical digestion gastric juice pepsin and HCl chemically digests protein
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Mucous cells: secrete a basic mucus that protects the epithelium against shear stress and acid
Parietal cells: secrete HCl
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Chief cells: secrete pepsin, a proteolytic enzyme
G cells: secrete the hormone gastrin
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HCl in Stomach Denatures proteins Activates pepsin
Kills bacteria; other microorganisms Dissolves minerals
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Stomach Mucosa Tissue that produces mucus
Mucus - a viscous fluid consisting of glycoproteins Mucus protects stomach lining from acidity of HCl
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1) The chemical digestion of which nutrient begins in the stomach?
2) The _____ glands secrete _____ which contains the enzyme _______which digests starch into _______________.
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Hydrochloric acid provides an optimum pH for the hydrolytic activity of gastric protease.
Under the influence of this enzyme, proteins are digested into polypeptides and dipeptides (amino aicds).
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How does the denaturation of proteins by HCL affect chemical digestion?
Denaturation of proteins by HCL exposes more surface area to enzymes, increasing the efficiency of digestion
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A Gastric Ulcer
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Ulcer open sore in the mucus membrane resulting from localized breakdown of tissues
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Bacteria cause ulcers
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The Stomach
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Mucous cells: secrete an alkaline mucus that protects the epithelium against shear stress and acid
Parietal cells: secrete hydrochloric acid! Chief cells: secrete pepsin, a proteolytic enzyme G cells: secrete the hormone gastrin
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1) The chemical digestion of which nutrient begins in the stomach?
2) The _____ glands secrete _____ which contains the enzyme _______which digests starch into _______________.
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Hydrochloric acid provides an optimum pH for the hydrolytic activity of gastric protease.
Under the influence of this enzyme, proteins are digested into polypeptides and dipeptides (amino aicds).
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Partially digested, liquefied food enters the small intestine.
The small intestine is a long, convoluted tube in which the major portion of food is digested. Partially digested, liquefied food enters the small intestine.
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Small intestine
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* The secretion from the gall bladder is bile.
Accessory structures, the gall bladder and pancreas, empty their secretions into the small intestine. * The secretion from the gall bladder is bile. Bile is produced in the liver and stored in the gall bladder.
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liver gall bladder
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liver gall bladder pancreas
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bile fat fat
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emulsification increases the surface area of fats for subsequent chemical action.
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Bile is not an enzyme, but a chemical that emulsifies (physically break apart) fat which serves to increase the surface area of fats for subsequent chemical action.
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pancreas
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Chemical Digestion The pancreas secretes several enzymes including intestinal protease, lipase, and amylase. Intestinal glands that line the intestinal wall secrete protease, lipase, and maltase.
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* The chemical digestion of proteins, lipids, and carbohydrates is completed in the small intestine.
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How do the end products of digestion get to our cells?
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esophagus liver Gall bladder Small intestine rectum
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villi
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Why does the small intestine have this structure?
microvilli Why does the small intestine have this structure? (folds, villi, microvilli)
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3 2 1 1 –intestinal fold 2 – villi 3 – microvilli
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Surface area of the small intestine
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overview till stomach http://www. youtube. com/watch
Villi - freezes towards the end villi
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Absorption In the Small Intestine
The lining of the small intestine contains numerous villi (small fingerlike projections) which increase the surface area of the small intestine to improve absorption.
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Capillaries and small lymphatic vessels, lacteals, extend into the villi.
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Villus (small intestine)
Lacteal Blood capillaries
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Villus (small intestine)
Lacteal Blood capillaries
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villi
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2) What are the three enzymes secreted by the pancreas?
1) The gall bladder and pancreas secrete _____and _____ into the small intestine for chemical digestion. 2) What are the three enzymes secreted by the pancreas?
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Fatty acids and glycerol are absorbed through the villi into the lacteals and are transported in the lymph. Monosaccharides and amino acids are absorbed through the villi and enter the capillaries to be transported to the liver where they are temporarily stored.
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From there, they are available for distribution by the blood.
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The breakdown of glycogen releases glucose for transport.
Glucose is temporarily stored as the polysaccharide glycogen (animal sugar) in the liver. The breakdown of glycogen releases glucose for transport.
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5. Large Intestine Undigested food and water enter the large intestine where excess water is absorbed as needed. During egestion, strong peristaltic action forces feces out through the anus.
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Functions of the Large Intestine
Reabsorbs water from food mass Absorbs vitamins Contains bacteria which: make vitamin K digest organic substances compete with dangerous bacteria in food Elimination (egestion) of undigested waste
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Feces Bacteria (50%) Cellulose Bile Mucous Dead cells
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B. Mechanism for Chemical Digestion
Hydrolysis is the splitting of large, insoluble molecules into small, soluble molecules with the addition of water. In organisms, this process is regulated by hydrolytic enzymes and is illustrated by the following:
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3 fatty acids + 1 glycerol maltose + water
maltase maltose + water glucose + glucose amino acid + amino acid + amino acid protease Proteins + water 3 fatty acids + 1 glycerol lipase lipids + water
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C. Some Malfunctions of the Digestive System
Ulcers are open sores in the interior wall of the digestive tract, most often in the stomach or the upper portion of the small intestine. The acid in gastric juice irritates the sores and causes pain or discomfort.
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Constipation is a condition in which the large intestine is emptied with difficulty.
Too much water is reabsorbed due to sluggish peristaltic movement and the solid waste hardens.
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Diarrhea is a gastrointestinal disturbance characterized by decreased water absorption and increased peristaltic activity of the large intestine. This results in increased, multiple, watery feces. This condition may result severe dehydration especially in infants.
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What is this?
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Appendicitis is an inflammation of the appendix due to infection.
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Human digestion (vocabulary)
nutrients digestion absorption fiber anus pharynx esophagus large intestine small intestine saliva salivary glands stomach rectum liver pancreas Peristalsis chyme villi
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Gallstones
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Gallstones are an accumulation of hardened cholesterol and/or deposits in the gall bladder.
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Gallstones
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Place these in the correct order
Ingestion Digestion Peristalsis More Digestion Absorption Egestion Peristalsis Egestion Ingestion Digestion More Digestion Absorption
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Design a controlled experiment to test the effect of pepsin concentration on the digestion of egg white Design an experiment to test the effect of substrate concentration on the activity of pepsin Design an experiment to find the optimum pH for the activity of pepsin
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Design an experiment to find the optimum pH for the activity of pepsin
HCL pepsin pepsin water HCL 1 capillary tube 1 capillary tube 1 capillary tube 1 capillary tube
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Design an experiment to test the effect of substrate concentration on the activity of pepsin
pepsin pepsin pepsin water HCL HCL HCL HCL 5 g protein g protein g protein g protein
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Design a controlled experiment to test the effect of pepsin concentration on the digestion of egg white 10 ml pepsin ml pepsin ml pepsin ml water 10 ml HCL 10 ml HCL ml HCL ml HCL 1 capillary tube 1 capillary tube 1 capillary tube 1 capillary tube with egg white
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