1. From: Lysophosphatidic Acid Promoting Corneal Epithelial Wound Healing by Transactivation of Epidermal Growth Factor Receptor
Invest. Ophthalmol. Vis. Sci ;48(2): doi: /iovs
Figure Legend:
Healing of scratch wound in cultured human corneal epithelial cells. Growth factor–starved THCE cell monolayer cultured in 12-well plates was injured with a sterile 0.1- to 10-μL pipet tip (original wound). Cells were then cultured in KBM (control), KBM containing LPA (5 μM), LPA with or without AG1478 (1 μM), or CRM197 (10 μg/mL) for 24 hours (day 1). (A) Photomicrographs show representative results of three independent experiments. (B) Changes in the extent of wound closure in THCE cells treated with different reagents. Results are presented as extent of healing (total covered as 100%) ± SD of three samples (**P <0.01, one way ANOVA).
Date of download: 12/20/2017
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