1. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
Hinge region of a SJM reagent valve. Inset on right shows the open SJM valve and the location of the b-datum line when the valve is closed.

2. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
Diagram of orifice plate chamber and steady flow loop

3. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
TAT concentration over time for the round orifices (p*<0.05, N=6)

4. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
TAT concentration over time for the slit orifices

5. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
Photographs of clot resulting from flow through the 200μm orifice. Clot is occluding the orifice and covering the periphery of the orifice. Total clot diameter was approximately 1.5mm.

6. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
TAT concentration over time for the platelet-depleted runs (p*<0.05, N=6). At all time points, significantly more TAT was produced in the normal experiments than in the platelet reduced experiments.

7. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
TAT concentration over time for the noncalcium infused runs (p*<0.05, N=6)

8. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
Hemoglobin concentration over time for the round orifices. Statistical significance was determined vs the 200μm orifice only (p*<0.05, N=6). Base line hemoglobin concentration at t=0 is indicated by the dotted line.

9. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
SEM pictures of the inlet clot under 1300× magnification (above pictures) and outlet clot under 1100× magnification (bottom left) and location away from the outlet clot under 1200× magnification (bottom right)

10. Date of download: 12/22/2017
Copyright © ASME. All rights reserved.
From: Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
J Biomech Eng. 2005;128(1): doi: /
Figure Legend:
Flow diagram detailing flow field through the round orifices