1. Day Date Reading Topic
T / pp (Ch. 6) C. elegans, model systems, and molecular genetics
Watch three Audio/Video handouts: 1A), 1B), and 1C
Th 9/5 Ch. 1 An introduction to developmental biology
T 9/10 QUIZ 1 (covers A/V Handouts 1A, 1B, and 1C) More introduction
Watch two Audio/Video handouts: Review of transcription regulation, Parts 1 and 2
Th 9/12 Ch. 3 Vertebrate life cycles
T 9/17 QUIZ 2 (covers A/V Handouts 2A and 2B) Vertebrate axes and germ layers
Th 9/19 CH. 4 Vertebrate axial patterning
T 9/24 More vertebrate body plan
Th 9/26 Ch. 5 Early patterning of vertebrate nervous systems
T 10/1 exam date changed
Th 10/3 Ch. 2 Molecular development of Drosophila
T 10/8 EXAM 1 Chapters 1, 3, 4, and pp
Lectures and Handouts
Th 10/10 Ch. 7 Plant development
On Thursday, 10/10, please bring a copy of the primary research article you have selected (or more than one if you haven’t decided) plus your notes on the article.

3. The Hox gene family are examples of homeotic genes.
Homeotic genes are genes that when mutant cause a change in the
spatial position of structures (change in address).
wild-type fruit fly
antennapedia mutant
Box 4A

4. The Hox gene family are examples of homeotic genes.
The Hox gene products give the positional address
along the Anterior-Posterior (A/P) axis in all animals.
Box 4A

5. The Hox gene family are examples of homeotic genes.
The Hox genes encode a family of paralogous proteins that are
sequence-specific DNA-binding transcription factors.

6. The Hox gene family are examples of homeotic genes.
The Hox proteins bind to response elements in the promoter
DNA of target genes. The DNA-binding domain of the protein
is called the homeodomain:

7. The Hox gene family are examples of homeotic genes.
Hox proteins work in a combinatorial manner to determine
A/P axis address.
Fig. 4.9

8. Figs. 4.27, 4.28

9. Fig. 5.3

10. Fig. 5.18

11. Fig. 5.20

12. Fig. 5.29

13. %ig. 5.31

14. Chapter 2: Drosophila embryogenesis

15. not in text

16. Genes to focus on during Drosophila embryogenesis
Bicoid
Hunchback
Even-skipped
Engrailed
Antennapedia
Hedgehog
Wingless
Gurken
Toll
Dorsal
Decapentaplegic
Short gastrulation

17. BIO305 Exam #1 Distribution
98 * A 97 96
95 ** A 94 93
92 * A 91
90 * A
89 *** A/A-
A/A- 87 B+
85 ** B+
84 * B+
83 * B+/B
82 ** B+/B B
80 *
79 * B 78 77 76 75
74 * B-
73 ** B-
72 *** B-/C+
71 * B-/C+
65 * C-
58 * D
47 * F