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TESTICULAR PURE CARTILAGINOUS TERATOMA: A CASE REPORT
D. Anestakis1, Ch. Tsompanidou2, I. Dimitriadis2, A. Kiziridou3, M. Lambropoulou4, P. Pavlidis5 1Department of Histopathology, Laboratory of Forensic Medicine and Toxicology, Aristotle University of Thessaloniki, Greece 2Department of Pathology, General Hospital of Thessaloniki “Agios Dimitrios”, Greece 3Department of Pathology, “Theagenio” Anticancer Institute Thessaloniki, Greece 4 Laboratory of Histology-Embryology, Democritus University of Thace, Greece 5 Laboratory of Forensic Medicine, Medical School, Democritus University of Thrace, Greece. OBJECTIVE: The monodermal teratomas are rare tumors of the testis which frequency ranges from 2,7-7%. The testicular pure cartilaginous differentiated teratoma is exceedingly rare, with only few cases previously descbribed. MATERIAL AND METHODS: A 45-year-old man visited our hospital complaining of painful swelling of the scrotum contents. Clinical examination and Imaging analysis revealed a mass in his right testis without evidence of metastatic disease. Blood chemistry showed normal levels of AFP and B-HCG. Therefore high inguinal orchiectomy was performed. Fig. 2 Testicular pure cartilaginous teratoma (X100) Fig. 3 Testicular pure cartilaginous teratoma (X400) RESULTS: The cut surface of the testis showed a 8Χ7Χ5 cm circumscribed, white-gray, solid, lobulated tumour located within the testicular parenchyma. Microscopically the tumour was entirely composed by mature cartilage. No intratubular germ cell neoplasia unclassified type was visible. The patient is alive with no evidence of disease at follow up of 21 months (Fig. 1, 2 and 3). CONCLUSION: The preoperative recognition of these tumors might help urologists approach the patients conservatively. Fig. 1 Monodermal teratoma composed solely of cartilage is rare. (X40) REFERENCES: 1. Herr HW and LaQuaglia MP: Management of teratoma. Urol Clin North Am 20 : , 1993 2. Mostofi FK : Testicular tumor epidemiologic, aetiologic, and pathologic features. Cancer 32: , 1973 3. Stevens MJ, Norman AR, Fisher C, et al. : Teratoma differentiated. Br J Urol 73: , 1994 4. Freedman LS, Parkinson MC, Jones WG, et al.: Histopathology in the prediction of relapse of patients with stage testicular teratoma treated by orchiectomy alone. J Clin Oncol 23: , 1984 5. Simmonds PD, Lee AHS, Theaker JM, et al. : Primary pure teratoma of the testis. J Urol 155 : , 1996 6. Leibovitch I, Foster RS, Ulbright TM, et al. : Adult primary pure teratoma of the testis. Cancer 75: , 1995
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