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DENİZ KAVGACI HALİME HELİN YILMAZ
TESTICULAR TUMORS DENİZ KAVGACI HALİME HELİN YILMAZ
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TNM STAGING American Joint Committee on Cancer (AJCC) T the extent of spread of the primary tumor to the tissues next to the testicle N number of lymph nodes affected M metastasis +/- S indicates the serum level of tumor markers (specific for certain types of testicular cancers)
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STAGING OF TESTICULAR CANCER
Stage I: tumor confined to the testis Stage II: spread to regional lymph nodes IIA: <2 cm in size or < 6 positive nodes IIB: 2-5 cm in size or > 6 positive nodes IIC: large and bulky abdominal mass, usually > 5-10 cm Stage III: spread beyond retroperitoneal nodes or above diaphragm or visceral disease Stage IV: hematogenous spread
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TREATMENT OF SEMINOMAS
Low grade (stage I and IIA) Radical inguinal orchiectomy Surveillance RT or single agent carboplatin High grade (stage >IIA) RPLND RT and/or CT
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NON-SEMINOMATOUS GERM CELL TUMOR
Management of men with NSGCT stage I depends on the presence of factors that present an increased risk of relapse: - Lymphovascular invasion - Predominance of an embryonal carcinoma component - A T3 or T4 primary tumor
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NSGCT TREATMENT
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REFERANCES THANK YOU…
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