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Partial regimen replacement with aripiprazole reduces serum prolactin in patients with a long history of schizophrenia: A case series  Keiko Naono-Nagatomo,

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Presentation on theme: "Partial regimen replacement with aripiprazole reduces serum prolactin in patients with a long history of schizophrenia: A case series  Keiko Naono-Nagatomo,"— Presentation transcript:

1 Partial regimen replacement with aripiprazole reduces serum prolactin in patients with a long history of schizophrenia: A case series  Keiko Naono-Nagatomo, MD, PhD, Hisao Naono, MD, Hiroshi Abe, PhD, Ryuichiro Takeda, MD, PhD, Hideki Funahashi, MD, PhD, Daisuke Uchimura, MD, PhD, Yasushi Ishida, MD, PhD  Asian Journal of Psychiatry  Volume 25, Pages (February 2017) DOI: /j.ajp Copyright © 2016 Elsevier B.V. Terms and Conditions

2 Fig. 1 Number of patients included in the analysis.
Asian Journal of Psychiatry  , 36-41DOI: ( /j.ajp ) Copyright © 2016 Elsevier B.V. Terms and Conditions

3 Fig. 2 Change in serum prolactin, body weight, and blood glucose over time. Serum prolactin level was decreased significantly at month 6 relative to month 0 (*p<0.05, Bonferroni). Body weight and blood glucose did not significantly differ over time. Asian Journal of Psychiatry  , 36-41DOI: ( /j.ajp ) Copyright © 2016 Elsevier B.V. Terms and Conditions

4 Fig. 3 Correlation between changes in serum prolactin relative to baseline at month 0. A significant negative correlation was observed (Spearman’s r=−0.99, p<0.01). Asian Journal of Psychiatry  , 36-41DOI: ( /j.ajp ) Copyright © 2016 Elsevier B.V. Terms and Conditions

5 Fig. 4 GAF evaluation scores. A one-way ANOVA and subsequent multiple comparison tests revealed significant score improvements at months 1, 3, and 6 relative to month 0 (*p<0.05, Bonferroni). Asian Journal of Psychiatry  , 36-41DOI: ( /j.ajp ) Copyright © 2016 Elsevier B.V. Terms and Conditions

6 Fig. 5 CGI-I evaluation scores. A one-way ANOVA and subsequent multiple comparison tests revealed significant score improvements at months 1, 3, and 6 relative to month 0 (*p<0.05, Bonferroni). Asian Journal of Psychiatry  , 36-41DOI: ( /j.ajp ) Copyright © 2016 Elsevier B.V. Terms and Conditions

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