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Copyright © 2017 McGraw-Hill Education. All rights reserved

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1 Copyright © 2017 McGraw-Hill Education. All rights reserved
Relationship between onset, duration, and spread of sensory anesthesia and onset, duration, and frequency of motor block produced by bupivacaine when employed as either a 0.5% or a 0.75% solution for intrathecal use. [Reprinted from Covino BG. Pharmacology of local anesthetic agents. In: Rogers MC, Tinker JH, Covino BG, et al, eds. Principles and Practice of Anesthesiology, Vol. 2. St. Louis, MO: Mosby Year Book; 1993:1240, with permission from Elsevier.] Source: Chapter 45. Pharmacology of Local Anesthetics*, Anesthesiology, 2e Citation: Longnecker DE, Brown DL, Newman MF, Zapol WM. Anesthesiology, 2e; 2012 Available at: Accessed: December 25, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved


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