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FIGURE 1 Flow chart of patient inclusion.
From: Relationships between iron dose, hospitalizations and mortality in incident haemodialysis patients: a propensity-score matched approach Nephrol Dial Transplant. Published online July 13, doi: /ndt/gfx209 Nephrol Dial Transplant | © The Author Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
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FIGURE 2 Kaplan–Meier survival curves of patients, grouped according to iron dose quartiles. Corresponding survival tables are shown. The P-value was calculated with the log-rank test. From: Relationships between iron dose, hospitalizations and mortality in incident haemodialysis patients: a propensity-score matched approach Nephrol Dial Transplant. Published online July 13, doi: /ndt/gfx209 Nephrol Dial Transplant | © The Author Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
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FIGURE 3 Association between high iron dose (across quartile groups) and all-cause mortality. The bars represent the HRs and their corresponding 95% CIs. Statistical comparisons were performed with the lowest iron dose quartile (<2.94) as reference. Crude model: only includes the iron dose quartile; demographics-adjusted model: crude model with the addition of age (years), CCI (units), VA, gender and BMI (km/m<sup>2</sup>); case-mix-adjusted CRP model: demographics-adjusted model with the addition of CRP (mg/L), haemoglobin (g/dL), Kt (L) and ESA dose (IU/kg/month); case-mix-adjusted albumin model: demographics-adjusted model with the addition of albumin (g/dL), haemoglobin (g/dL), Kt (L) and ESA dose (IU/kg/month); and adjusted model: final model, including both albumin and CRP. The probability that each ratio is significantly different from its reference value is indicated by a symbol near the ratio: <sup>#</sup>P < 0.001; *P < 0.05; no symbol indicates no significant difference. From: Relationships between iron dose, hospitalizations and mortality in incident haemodialysis patients: a propensity-score matched approach Nephrol Dial Transplant. Published online July 13, doi: /ndt/gfx209 Nephrol Dial Transplant | © The Author Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
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FIGURE 4 Association between high iron dose (across quartile groups) and all-cause hospitalization and cardiovascular hospital admissions. The bars represent the ORs and their corresponding 95% CIs. Statistical comparisons were performed with the lowest iron dose quartile (<2.94) as reference. Crude model: only includes the iron dose quartile; demographics-adjusted model: crude model with the addition of age (years), CCI (units), VA, gender and BMI (km/m<sup>2</sup>); case-mix-adjusted CRP model: demographics-adjusted model with the addition of CRP (mg/L), haemoglobin (g/dL), Kt (L) and ESA dose (IU/kg/month); case-mix-adjusted albumin model: demographics-adjusted model with the addition of albumin (g/dL), haemoglobin (g/dL), Kt (L) and ESA dose (IU/kg/month); and adjusted model: final model, including both albumin and CRP. The probability that each ratio is significantly different from its reference value is indicated by a symbol near the ratio: <sup>#</sup>P < 0.001; <sup>+</sup>P < 0.01; *P < 0.05; no symbol indicates no significant difference. From: Relationships between iron dose, hospitalizations and mortality in incident haemodialysis patients: a propensity-score matched approach Nephrol Dial Transplant. Published online July 13, doi: /ndt/gfx209 Nephrol Dial Transplant | © The Author Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
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FIGURE 5 Kaplan–Meier survival plots and HRs of patients grouped according to the iron dose; results are shown before and after PSM. Survival curves show groups treated with ≤5.65 mg/kg/month (black) or ≥5.66 mg/kg/month (grey), and their corresponding survival tables. The P-values were calculated with the log-rank test; HRs are accompanied by the corresponding 95% CIs. From: Relationships between iron dose, hospitalizations and mortality in incident haemodialysis patients: a propensity-score matched approach Nephrol Dial Transplant. Published online July 13, doi: /ndt/gfx209 Nephrol Dial Transplant | © The Author Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
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