1. Nicholas Inston University Hospital Birmingham seconded at Guerbet Group MER 7

2. Background Born In UK Educated in the UK
BMedSci University of Nottingham
MBChB University of Nottingham
PhD in Medicine University of Birmingham 2002

3. Project WP2 Literature data mining: systematic and narrative reviews
MER7 Seconded from University Hospital Birmingham to Guerbet Group
Supervisor of Julien Alshakarchi and Zaib Khawaja (alongside Eric Lancelot)
Other ESR secondees involved in WP2 Deirdre Cassidy
WP2: Data mining and prospective data sharing
Literature data mining: systematic and narrative reviews
UHB Data mining: Outcomes e.g. elderly, training, biological markers..
Data synthesis: Questionnaire/Survey and guidelines appraisal

4. Training
Experience of working with academic and industry partners from different disciplines
Experience in EU grant process and administration
Working closely with a multi-national company (Guerbet/VFT)
Training in statistical methodologies
Attendance at courses and conferences
‘Controversies and Updates in Vascular Surgery Congress’ in Paris January 2015
European Vascular Course in Maastricht March 2015
Congress of the Vascular Access Society in Barcelona April 2015
Vascular access society Britain and Ireland Sept 2014

5. Collaboration European Renal Association
European Best Practice Guidelines group
Systematic Review Statistics workshop (Paris)
EuroDOPPs study
VAS 2015 – presented in “Translational Science” session
Collaboration with French surgeons (PB LT)
Cochrane group
UK RA/BRS HD research advisory group

6. Presentations BSIR 2014: VAS 2015:
Outcomes of the Haemodialysis Reliable Outflow Device (HeRO) for vascular access (Poster)
VAS 2015:
Exhausted vascular access: a proposed classification (Poster)
Pre-operative biological markers in predicting outcome of fistula formation (Poster)
Systematic review of the ulnar-basilic arteriovenous fistula for haemodialysis (Poster)
Assessing UK trends in vascular access imaging for haemodialysis patients – results from REDVASQI (Poster)
Preoperative imaging in arteriovenous fistula formation: a systematic review (Poster)
Revisiting the risks of contrast enhanced MRI in vascular access imaging (Poster)
Systematic review and meta-analysis of vascular access outcomes in elderly patients (Poster)
Near-infrared spectroscopy (NIRS) in vascular access. A new application for Invos Spectra (Poster)
Arterial stiffness correlates with arteriovenous fistula outcomes (Oral - Presenter)

7. Publications
Julien Al Shakarchi, Graeme Houston; Robert Jones; Nicholas Inston. A Review on the Hemodialysis Reliable Outflow (HeRO). EJVES 9988R In press
J Al Shakarchi, A Khawaja, D Cassidy, JG Houston, N Inston. Efficacy of the ulnar-basilic arteriovenous fistula for haemodialysis: A systematic review. Journal of Vascular Access JVA-D In press
Julien Al Shakarchi and Nicholas Inston. Timing of cannulation of arteriovenous grafts: are we too cautious? Clin Kidney J (2015) 0: 1–3 doi: /ckj/sfu146
Damian G. McGrogan, Alexander P. Maxwell, Aurang Z. Khawaja and Nicholas G. Inston. Current tools for prediction of arteriovenous fistula outcomes. Clin Kidney J (2015) 0: 1–8 doi: /ckj/sfv019
Inston NG Long-term results of biological grafts for haemodialysis vascular access. J Vasc Access Mar 9;16 Suppl 9:82-6.
McGrogan DG, Field MA, Maxwell AP, Marie Y, Inston NG. Patient survival following arteriovenous fistula formation. J Vasc Access Jan 27;0(0):0. doi: /jva [Epub ahead of print]
McGrogan DG, Field MA, Inston NG. Survival following arteriovenous fistula formation: are grafts indicated in the elderly? J Vasc Access Aug 27;0(0):0. doi: /jva [Epub ahead of print]
McGrogan DG, Maxwell AP, Inston NG, Krishnan H, Field M. Preserving arteriovenous fistula outcomes during surgical training. J Vasc Access Aug 27;0(0):0. doi: /jva [Epub ahead of print]
Marie Y, Guy A, Tullett K, Krishnan H, Jones RG, Inston NG. Patterns of blood flow as a predictor of maturation of arteriovenous fistula for haemodialysis. J Vasc Access May-Jun; 15 (3):169-7

8. Presentations
Yazin Marie, Nuor N S Jamil, Helen Caldwell, Rebecca Telfer, Souad Messahel, Nicholas G Inston CASPASE-3 EXPRESSION IS REDUCED BY FLOW IN A HUMAN WHOLE VEIN PULSATILE FLOW MODEL 12: :02 9th Congress of VAS, April Barcelona 2015
Damian Mcgrogan, Mark Jesky, Paul Cockwell, Stephanie Stringer, Nicholas Inston 18: :07 ARTERIAL STIFFNESS CORRELATES WITH ARTERIOVENOUS FISTULA OUTCOMES 9th Congress of VAS, April Barcelona 2015
P41 ASSESSING UK TRENDS IN VASCULAR ACCESS IMAGING FOR HAEMODIALYSIS PATIENTS – RESULTS FROM REDVASQI Aurangzaib Khawaja, Deirdre Cassidy, Julien Al Shakarchi, Damian Mcgrogan, Robert G. Jones, Nicholas Inston 9th Congress of VAS, April Barcelona 2015
p42 SYSTEMATIC REVIEW AND META-ANALYSIS OF VASCULAR ACCESS OUTCOMES IN ELDERLY PATIENTS Damian McGrogan, Julien Al-Shakarchi, Aurangzaib Khawaja, Jay Nath, Mel Field, Nicholas Inston. 9th Congress of VAS, April Barcelona 2015
p62 EARLY EXPERIENCE WITH VIABAHN STENT-GRAFTS TO TREAT CEPHALIC ARCH STENOSIS IN HEMODIALYSIS PATIENTS WITH IPSILATERAL ARTERIOVENOUS FISTULAS Robert Jones, Peter Riley, Andrew Willis, Nicholas Inston, Aurangzaib Khawaja 9th Congress of VAS, April Barcelona 2015
p69 NEAR-INFRARED SPECTROSCOPY (NIRS) IN VASCULAR ACCESS. A NEW APPLICATION FOR INVOS®SPECTRA Damian Mcgrogan, Julien Al-Shakarchi, Aurangzaib Khawaja, Jay Nath, Mel Field, Nicholas Inston 9th Congress of VAS, April Barcelona 2015
p74 EXHAUSTED VASCULAR ACCESS: A PROPOSED CLASSIFICATION Julien Al Shakarchi, Jay Nath, Robert G. Jones, Nicholas Inston 9th Congress of VAS, April Barcelona 2015
p77 PRE-OP GROUP AND SAVE SAMPLES ARE UNNECESSARY FOR ROUTINE ARTERIO-VENOUS FISTULA SURGERY James Winchester, Njeri Ibrahim, Devika Sookloll, Nick Inston, Damian McGrogan. 9th Congress of VAS, April Barcelona 2015
p89 PRE-OPERATIVE BIOLOGICAL MARKERS IN PREDICTING OUTCOME OF FISTULA FORMATION Julien Al Shakarchi, Damian McGrogan, Aurangzaib Khawaja, Melanie Field, Nicholas Inston 9th Congress of VAS, April Barcelona 2015

9. Presentations cont…
p92 PREOPERATIVE IMAGING IN ARTERIOVENOUS FISTULA FORMATION: A SYSTEMATIC REVIEW Deirdre B. Cassidy Aurangzaib Khawaja, Nicholas Inston, Julien Alshakarchi, Shona Matthew, J. Graeme Houston 9th Congress of VAS, April Barcelona 2015
p93 PREOPERATIVE EXAMINATION FOR ARTERIOVENOUS ACCESS IN HAEMODIALYSIS: INSIGHT INTO CLINICAL PRACTICE GUIDELINES Deirdre B. Cassidy, Aurangzaib Khawaja, Javaad Ayub, Nicholas Inston, Eric Lancelot, Shona Matthew, J Graeme Houston 59th Congress of VAS, April Barcelona 2015
p103 SYSTEMATIC REVIEW OF THE ULNAR-BASILIC ARTERIOVENOUS FISTULA FOR HAEMODIALYSIS Julien Al Shakarchi, Aurangzaib Khawaja, Deirdre B. Cassidy, Graeme Houston, Nicholas Inston 9th Congress of VAS, April Barcelona 2015
p105 RE-VISITING THE RISKS OF CONTRAST ENHANCED MRI IN VASCULAR ACCESS IMAGING Aurangzaib Khawaja, Deirdre B. Cassidy, Julien Alshakarchi, Damian McGrogan, Nicholas Inston, Robert G. Jones 9th Congress of VAS, April Barcelona 2015
Plenary session: The science of vascular access: new frontiers. Nicholas Inston May 1st VASA 2014 Dallas.
1.10 ‘Fistula Fast’ - Initial Experience from a New, Rapid Access Arteriovenous Fistula Pathway. Damian McGrogan; Yazin Marie; Susan Freckleton; Helen Eddington, PhD; Clara Day; Nicholas Inston VASA 2014, Dallas May 2014
4.6 Cutting Angioplasty Balloon in Native AV Fistulas - A Seven Year Experience Aurangzaib Khawaja; Robert Jones; Nicholas Inston; Andrew Willis; Ian MacCafferty; Peter Riley VASA 2014, Dallas May 2014

10. Future
ERBP as an lead coach in updating clinical guidelines (Wim Biesen)
Supervisor – EURODOPPS project (Dr Sabine Van Veer)
Development of a collaborative research group for the Vascular access societies
Maintain supervision of higher degrees of ReDVA fellows
Further grant applications
Council of Vascular Access Society
President Vascular Access Society Britain and Ireland