1. OSF Improves the Distributed Pharmaceutical Analysis Lab (DPAL)
Margaret Berta

2. Substandard Pharmaceuticals
-substandard pharmaceuticals are medications with >90% of stated API
-widespread problem in developing countries
-estimated that >30% of pharmaceuticals sold in developing countries are falsified or substandard
-often medical regulatory agencies do not have the resources to maintain post-market quality control
-graphic showing the number of substandard pharmaceutical cases reported from
Johnston, A., & Holt, D. (2014, Aug). Substandard Drugs: a Potential Crisis for Public Health. Br. J. Clin. Pharmacol., 78(8),

3. Effective Pharmaceutical Regulation
-adequate funding
-trained personnel
-analytical resources
-governmental support (Medical Regulatory Authority) (MRA)

4. Distributed Pharmaceutical Analysis Lab (DPAL)

5. Program Set-Up Considerations
-data security
-communication
-data sharing
-user experience

6. OSF Registrations for Data Preservation
Data Security
OSF Registrations for Data Preservation
OSF Registrations
Non-editable Version
Citable Reference
Alternative Backup
-individual pages but with data submission forms
-forms  spreadsheet

7. Internal “peer review” to maintain quality
Communication
Internal “peer review” to maintain quality
DPAL Project
Read-Only
-individual pages but with data submission forms
-forms  spreadsheet

8. Institutional data with controlled results submission
Data Sharing
Institutional data with controlled results submission
Cumulative Results
Restricted Access Forms
View-Only Spreadsheets
Institution Component
-individual pages but with data submission forms
-forms  spreadsheet

9. HPLC Methodology Manual
Usability
Informational resources for target audiences
HPLC Methodology Manual
Students
Instructors
-individual pages but with data submission forms
-forms  spreadsheet

10. DPAL System Set-Up on OSF Application by Participants
Assessment
DPAL System Set-Up on OSF
Application by Participants
-system structure but for effective project, we need everyone to actually use it

11. Questions?