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Figure 1 Multidimensional scaling plots
Figure 1 Multidimensional scaling plots. ( A ) The distribution of the dogs from Denmark, Sweden, Germany, England, and France. ( B ) The distribution of case and control dogs. (This figure appears in color in the online version of Journal of Heredity.) From: Identification of 2 Loci Associated with Development of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels J Hered. 2011;102(Suppl_1):S62-S67. doi: /jhered/esr041 J Hered | © The American Genetic Association All rights reserved. For permissions, please
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Figure 2 Genome-wide association of SNP markers to MMVD in CKCS
Figure 2 Genome-wide association of SNP markers to MMVD in CKCS. ( A ) GWAS of 139 cases and 102 controls reveals an association of MMVD to CFA 13q2.2.3 ( P<sub>genome</sub> = 6.8 × 10 <sup>−3</sup> ) and CFA 14q1.3 ( P<sub>genome</sub> = 7.9 × 10 <sup>−4</sup> –2.3 × 10 <sup>−2</sup> ). ( B ) GWAS of the 2 largest subpopulations (108 cases and 95 controls) reveals an association of MMVD to CFA 13q2.2.3 ( P<sub>genome</sub> = 4.0 × 10 <sup>−5</sup> –4.7 × 10 <sup>−3</sup> ) and CFA 14q1.3 ( P<sub>genome</sub> = 1.7 × 10 <sup>−2</sup> ). From: Identification of 2 Loci Associated with Development of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels J Hered. 2011;102(Suppl_1):S62-S67. doi: /jhered/esr041 J Hered | © The American Genetic Association All rights reserved. For permissions, please
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