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Sickle cell anemia. This peripheral blood smear exhibits sickled cells (arrowheads). Sickled cells pass through the vasculature with more difficulty, becoming.

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Presentation on theme: "Sickle cell anemia. This peripheral blood smear exhibits sickled cells (arrowheads). Sickled cells pass through the vasculature with more difficulty, becoming."— Presentation transcript:

1 Sickle cell anemia. This peripheral blood smear exhibits sickled cells (arrowheads). Sickled cells pass through the vasculature with more difficulty, becoming lodged in capillaries and other small vessels and leading to tissue ischemia. Ischemia in turn promotes additional sickling of the red blood cells. Wright-Giemsa, 1000×. Source: Chapter 12. Hematopathology, Pathology: The Big Picture Citation: Kemp WL, Burns DK, Brown TG. Pathology: The Big Picture; 2008 Available at: Accessed: December 27, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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