1. Image Challenge Q:
What is the diagnosis in this 42-year-old man with bone pain?
1. Hypervitaminosis A
2. Gaucher's disease
3. Multiple myeloma
4. Osteopetrosis
5. Thalassemia minor

2. Image Challenge Q:
What is the diagnosis in this 42-year-old man with bone pain?
Answer:
Gaucher's disease
Bone involvement is common in Gaucher's disease. Flaring of the distal femur, the so-called Erlenmeyerflask deformity, is a classic sign of the disease. Marrow infarctions are also present throughout. Secondary osteoarthritic changes are due to subchondral bony collapse resulting from osteonecrosis.