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Dr Dawood Quiz questions
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A HIV infected patient with newly diagnosed extra-pulmonary tuberculosis and a CD4 count of 36 cells/ul: Should start antiretroviral therapy (ART) immediately together with TB therapy ART should be deferred for 2 weeks after commencing TB therapy ART should be deferred for 8 weeks after commencing TB therapy TB therapy should be deferred for 2 weeks after ART is started TB therapy should be deferred in order to avoid possible immune reconstitution syndrome
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In a pregnant women co-infected with HIV and TB requiring antiretroviral therapy (ART)
TB treatment is the priority Nevirapine may be safely used in pregnancy and TB Streptomycin should form part of the re-treatment TB regimen Nevirapine does not have any drug – drug interactions with standard TB therapy Cotrimoxazole is contraindicated
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With regard to the diagnosis of tuberculosis (TB) in the HIV infected patient:
Smear negative Pulmonary TB (PTB) is common in patients with advanced immunosuppression Lymph node aspiration is not a helpful diagnostic procedure Mycobacterial blood cultures have a poor yield in patients with severe immune suppression and disseminated TB Pulmonary TB in HIV infection should always be treated with a 12 month course of anti-tuberculous treatment The standard therapy for Pulmonary TB is isoniazid, rifampicin, ethambutol and pyrazinamide for 2 months followed by isoniazid and rifampicin for 4 months The following test are used to diagnose TB
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