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RBC membrane disorders

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1 RBC membrane disorders
RBC membrane disorders. The normal erythrocyte morphology is a biconcave disc, but RBC membrane defects cause an abnormal morphologic appearance among circulating erythrocytes, which leads to hemolytic anemia. A: Spherocytes that are small dense cells lacking central pallor. B: Elliptocytes that have an oval elongated shape. C: Spheroelliptocytosis featuring cells with features of both spherocytes and elliptocytes. D: Hereditary pyropoikilocytosis with bizarre morphology, including small triangular erythrocytes. Source: Chapter 433. Hemolytic Anemia, Rudolph's Pediatrics, 22e Citation: Rudolph CD, Rudolph AM, Lister GE, First LR, Gershon AA. Rudolph's Pediatrics, 22e; 2011 Available at: Accessed: December 28, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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