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Fig. 1. Genetic affinity and population structure of Xinjiang’s Uyghur (XJU). (A) Distribution map of XJU samples. The abbreviated name of each region.

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Presentation on theme: "Fig. 1. Genetic affinity and population structure of Xinjiang’s Uyghur (XJU). (A) Distribution map of XJU samples. The abbreviated name of each region."— Presentation transcript:

1 Fig. 1. Genetic affinity and population structure of Xinjiang’s Uyghur (XJU). (A) Distribution map of XJU samples. The abbreviated name of each region was colored according to figure 1C. No samples were collected from Altay. (B) PCA of 951 XJU with reference populations from Central Asia Siberia, East Asia, South Asia, and West Eurasia. (C) PCA of 679 XJU individuals from 11 regions (samples from Aksu (AKS), Bayingolin1 (BAY1), and Urumqi (URU) were excluded). (D) Effective migration rates of XJU individuals based on EEMS analysis with 700 demes. Dark blue color indicates higher migration rate, whereas brown color indicates lower migration rate. Red dashed line indicates the putative genetic barrier. From: Genetic History of Xinjiang’s Uyghurs Suggests Bronze Age Multiple-Way Contacts in Eurasia Mol Biol Evol. 2017;34(10): doi: /molbev/msx177 Mol Biol Evol | © The Author Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please

2 Fig. 2. Ancestry makeup and variations in admixture proportion within XJU. (A) ADMIXTURE results of XJU with West Eurasia, South Asia, East Asia, and Central Asia Siberia populations at K = 4 (in order to show a full picture of Eurasian populations, all populations of the four major ancestries (including representative populations) were included.). Proportion of each ancestry in XJU was highlighted with a pie chart. Height of the bar is proportional to admixture proportion. (B) Admixture proportions of the four major ancestries in regional XJU based on ADMIXTURE analysis in figure 2A. Red dashed line indicates the genetic barrier from EEMS analysis in figure 1D. (C) Correlations between proportions of four major ancestries and latitudes as well as longitudes of XJU across regions. Grey region indicate 95% confidence region for each regression fit. EA = East Asia; SA = South Asia; SIB = Siberia; WE = West Eurasia. From: Genetic History of Xinjiang’s Uyghurs Suggests Bronze Age Multiple-Way Contacts in Eurasia Mol Biol Evol. 2017;34(10): doi: /molbev/msx177 Mol Biol Evol | © The Author Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please

3 Fig. 3. Population admixture and admixture history of XJU
Fig. 3. Population admixture and admixture history of XJU. (A) The most likely admixture topology of the four major ancestries in XJU based on Admixture History Graph (AHG) results. Ancestries represented as colored balls were as follows: EA (Red); SIB (Gold); EA-SIB (Plum); WE (Blue); SA (Green); WE-SA (Cyan). (B) Admixture time of EA-SIB admixture, WE-SA admixture, and West–East admixture in XJU by MultiWaver. Representative populations (represented as colored balls) used in MultiWaver were as follows: EA = Atayal; SIB = Nganasan; EA-SIB = Hezhen; WE = Sardinian; SA = Mala; WE-SA = Tajik_pomiri. Representative populations were selected according to ADMIXTURE results with their major components (>10%) limited to representative ancestries. XJU from different regions in Xinjiang were inferred separately. (C) Schematic map showing the possible admixture model of XJU. Arrows in different colors indicate ancestral sources and directions of the gene flow. From: Genetic History of Xinjiang’s Uyghurs Suggests Bronze Age Multiple-Way Contacts in Eurasia Mol Biol Evol. 2017;34(10): doi: /molbev/msx177 Mol Biol Evol | © The Author Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please

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