1. GUT PHYSIOLOGY Absorption 1 Dr. Jack Grider Rm 12-004 Sanger Hall
2009

2. Digestion & Absorption

3. Digestion & Absorption
Brush
Border

4. Digestion & Absorption
Absorption from the lumen
is impeded by the unstirred
layer and the apical
membrane of the enterocyte.

5. Digestion & Absorption
Two routes of absorption
Are available for
movement of nutrient
across the apical
membrane of the
enterocyte:
- Paracellular
Transcellular
active & passive

6. Digestion & Absorption
Transcellular route of absorption utilizes multiple mechanisms to bypass the membrane barrier.

7. Digestion; Carbohydrate
Ingestion of large glucose polymers as starches
and some sucrose (Glu-Fru) and lactose (Glu-Gal).
Digestions occurs at level of
Oral cavity: ptyalin
Stomach
Small intestine: pancreatic amylase
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8. Digestion & Absorption: Carbohydrate

9. Digestion & Absorption: Carbohydrate

10. Digestion & Absorption: Carbohydrate
GLUT5
SGLT1
GLUT2

11. Digestion & Absorption: Carbohydrate

12. Digestion: Protein Ingestion: long chains of amino acids as protein
Endogenous: enzymes, mucus, dead cells
Digestion:
Stomach: Pepsin (low pH)
Intestine: pancreatic peptidases
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13. Digestion & Absorption: Protein

14. Digestion & Absorption: Protein

15. Digestion & Absorption: Protein

16. Digestion & Absorption

17. Digestion & Absorption

18. Digestion & Absorption