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9-1 How come you look like you?
It’s in your genes!
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Transmission of characteristics from parents to offspring is called ___________________.
The STUDY of how those characteristics are passed on from one generation to the next is called ___________________ heredity Genetics
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Gregor Mendel The Father of Genetics is _________________,
The Father of Genetics is _________________, a monk whose study of genetic traits was the beginning of our understanding about how genes work. Gregor Mendel
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Mendel designed experiments using _________________________.
He looked at different observable CHARACTERISTICS or ______________ Pea plants TRAITS
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Pea Characteristics
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A plant that ALWAYS produces offspring with a certain trait are called ___________ for that trait.
PURE
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Remember all body cells have 2 copies of every gene, so to breed pure the 2 parent gene choices must be the_________. SAME red flower alleles TWO
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PURE white flowered plants have ______ WHITE flower alleles TWO
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Mendel combined genes from 2
PURE parent plants and recorded the kinds of ___________ produced. In his experiments the 1st plants crossed were called the ____ generation. ( P is for parental) offspring P1
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GENETIC EXPERIMENTS P1 ____ generation (parental) ____ generation (filial=offspring) ___ generation F1 F2
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GENETIC EXPERIMENTS Image modified from:
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When Mendel crossed PURE PLANTS with 2 choices for a trait:
He found 1. ___________________________________ BUT 2. ___________________________________ Only one trait showed in the F1 generation Missing trait reappeared in the F2 generation in a 3 to 1 ratio
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Mendel decided that there must be a_______ of “factors” controlling each trait and that one factor must be able to _______ the other. pair hide
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We now know that Mendel’s “factors” are _________ carried
on the pair of________________ _________________ genes homologous chromosomes
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_______________ are different gene choices for a trait. ALLELES
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DOMINANT __________________ = An allele that MASKS the presence of another allele __________________ = An allele that IS MASKED BY the presence of another allele RECESSIVE
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WHAT DOES MEIOSIS HAVE TO DO WITH IT?
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MENDEL’S LAWS SEGREGATION LAW OF ____________________
The pair of factors is segregated (or separated) during the formation of gametes. SEGREGATION Image modified from:
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LAW OF __________________________
the factors are distributed to gametes independently of other factors INDEPENDENT ASSORTMENT Image modified from:
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MEIOSIS MENDEL’s LAWS of SEGREGATION & INDEPENDENT ASSORTMENT
happen because of the way the chromosomes move during __________________ MEIOSIS
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GENETIC CROSSES 9-2
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DOMINANT/RECESSIVE T t capital lower-case NOT S for short
Dominant gene is represented by a ____________ letter. (usually the first letter of the trait) Recessive gene is represented by the SAME _________________ letter. EX: Tall = ______ Short =______ capital lower-case T t NOT S for short
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HOMOZYGOUS HETEROZYGOUS
When both alleles in the pair are the SAME the organism is _______________ or __________ EX: TT or tt When both alleles in the pair are DIFFERENT the organism is _________________ or _____________ Ex: Tt HOMOZYGOUS PURE HETEROZYGOUS HYBRID
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PHENOTYPE/GENOTYPE The genetic makeup of an organism is its _____________ The appearance of an organism is its _____________ GENOTYPE PHENOTYPE
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Animation from: PUNNETT SQUARES are used to show possible offspring of a cross between 2 parents Parent genes go at top and on left side Boxes show possible combinations
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PROBABILITY ____________________ is the likelihood that a specific event will occur It can be written as a: Fraction 1/4 Percent 25% Ratio 1:3
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IN PEA PLANTS Tall is dominant over short TALL = ____ SHORT = ____ T t
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PURE TALL parent What genes can it give?
T T _________ HOMOZYGOUS T T
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T T
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PURE SHORT parent What genes can it give?
t t _________ HOMOZYGOUS t t
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T T t t T t T t T t T t ALL of the offspring 4/4 100% will be Tt TALL
GENOTYPE _____ PHENOTYPE _______
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HYBRID TALL parent What genes can it give?
T t _________ HETEROZYGOUS T t
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T t
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T t T t T t T T T t t t GENOTYPES ¼ = _____ TT ½ = _____ Tt tt 3/4 1/4
TALL PHENOTYPES _______ ____________ _______ ____________ 1/4 SHORT
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MAKING A CROSS with only ONE gene trait = ____________________
MONOHYBRID CROSS A Punnett square for a MONOHYBRID CROSS looks like this:
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TESTCROSS used to tell what genes an organism has
Cross an UNKNOWN parent with a ____________________________ and see results Offspring give a clue about the unknown parent’s genes HOMOZYGOUS RECESSIVE
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TESTCROSS used to tell what genes an organism has
Example: The genes of a TALL PARENT are UNKNOWN - COULD HAVE _____ TT Tt
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TESTCROSS Tt tt t Tt Tt 50% will be TALL All offspring will
50% will be SHORT All offspring will be TALL
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DEAF DOGS Deafness in dogs is caused by a recessive allele. Deaf dogs have the genotype dd. A HEARING dog could have 2 possible GENOTYPES ______ ______ How do we tell which one it is? Dd DD
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TESTCROSS DEAF PARENT WITH PURE HEARING PARENT
D D D d d Hear Hear Hear Deaf Hear Deaf d If you get some deaf puppies, you know parent was Dd.
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GENES are more complicated than MENDEL thought
Some traits have more than two allele choices EX: eye color
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GENES are more complicated than MENDEL thought
Some traits are determined by more than one gene EX: Human height
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GENES are more complicated than MENDEL thought
Traits determined by more than one gene have lots of “in-between” phenotypes There aren’t just SMART people and DUMB people…. there is a whole range of intelligences in-between
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GENES are more complicated than MENDEL thought
KINDS OF DOMINANCE ____________________ COMPLETE DOMINANCE INCOMPLETE DOMINANCE CO-DOMINANCE
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COMPLETE DOMINANCE Dominant allele masks the recessive one
Recessive allele returns in a 3:1 ratio in the F2 generation
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INCOMPLETE DOMINANCE Don’t see expected 3:1 ratio in F2 generation
Organisms with one dominant and one recessive allele show a blended in-between trait
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INCOMPLETE DOMINANCE ALLELES BLEND to produce an INTERMEDIATE
PHENOTYPE Don’t see the expected 3:1 ratio in the F2 generation
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CO-DOMINANCE Both traits are expressed at same time (NO BLENDING) in heterozygote Has BOTH RED hair and WHITE hair
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CO-DOMINANCE Both traits are expressed together (NO BLENDING) in heterozygote Persons with an A gene AND a B gene have blood type AB
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BLOOD TYPES have more than 2 allele choices
Proteins with SUGARS attached help cells recognize ___________ Called _______________ “self” GLYCOPROTEINS
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BLOOD TYPES have more than 2 allele choices
The protein and sugar that is attached is determined by genes Allele choices are: _____ ____ ____ B A O
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BLOOD TYPES An A gene tells the cell to put “A” glycoproteins
on its surface
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BLOOD TYPES An B gene tells the cell to put a
different “B” glycoprotein on its surface
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BLOOD TYPES An O gene tells
the cell NOT to put anything on the surface
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A and B are CO-DOMINANT A cell with an A and a B gene has BOTH
glycoproteins on its surface
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BLOOD TYPES & ALLELES ALLELE BLOOD TYPE AA A AO BB B BO OO O AB
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BLOOD TYPES IMMUNE SYSTEM ATTACKS! YOU’RE NOT DIFFERENT FROM ME!
YOU ARE NOT ME! IMMUNE SYSTEM ATTACKS! YOU’RE NOT DIFFERENT FROM ME! Body images modified from:
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BLOOD TYPES IMMUNE SYSTEM ATTACKS! YOU’RE NOT DIFFERENT FROM ME!
YOU ARE NOT ME! IMMUNE SYSTEM ATTACKS! YOU’RE NOT DIFFERENT FROM ME! Body images modified from:
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BLOOD TYPES YOU’RE LIKE ME! IMMUNE SYSTEM ATTACKS!
YOU ARE NOT ME! IMMUNE SYSTEM ATTACKS! YOU’RE LIKE ME! Body images modified from:
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BLOOD TYPES YOU’RE NOT DIFFERENT FROM ME!
O can donate to EVERY BLOOD TYPE = UNIVERSAL DONOR! Nothing on surface to recognize as “NOT SELF” YOU’RE NOT DIFFERENT FROM ME! Body images modified from:
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BLOOD TYPES AB can RECEIVE FROM EVERY BLOOD TYPE = UNIVERSAL RECIPIENT
Body image modified from:
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BLOOD TYPE FREQUENCY IN USA
40% B 10% AB 4% O 46%
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OTHER BLOOD TYPES Rh Rh-
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OTHER BLOOD TYPES NO PROBLEMS IF: MOM is + & BABY is -
MOM & BABY are both + Imagea modified from:
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OTHER BLOOD TYPES PROBLEMS IF: MOM is - & BABY is +
1st baby OK but few baby cells entering mom’s bloodstream put mom’s immune system on alert for + cells. Next + baby, mom’s immune system can attack baby as it is growing Shot after 1st birth prevents alert Imagea modified from:
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DIHYBRID CROSSES (2 traits)
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MAKING A CROSS with TWO gene traits = ____________________
DIHYBRID CROSS A Punnett square for a DIHYBRID CROSS looks like this:
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HOMOZYGOUS ROUND YELLOW
HOMOZYGOUS WRINKLED GREEN X r r y y R R Y Y
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POSSIBLE GAMETES?
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POSSIBLE GAMETES?
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RY RY RY RY RrYy ROUND YELLOW ry ry ry ry
RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RY RY RY RrYy 100% of offspring = _______ genotype _______________________ phenotype ROUND YELLOW
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HETEROZYGOUS ROUND YELLOW
X R r Y y R r Y y
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POSSIBLE GAMETES?
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9:3:3:1 9 RY 3 ry 3 rY Ry Sign of a heterozygous dihybrid cross is a
____ Round & Yellow ____ Round & green ____ Wrinkled & yellow ____ wrinkled & green 9 RY RRYY RrYy RrYY RRYy RrYy rryy rrYy Rryy RrYY RrYy rrYY rrYy RrYy Rryy rrYy RRyy 3 ry 3 rY 1 Ry Sign of a heterozygous dihybrid cross is a _____________ ratio in offspring. 9:3:3:1
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9:3:3:1 9 3 3 1 ____ DOMINANT TRAIT 1 ; DOMINANT TRAIT 2
____ DOMINANT TRAIT 1; RECESSIVE TRAIT 2 ____ RECESSIVE TRAIT 1; DOMINANT TRAIT 2 ____ RECESSIVE TRAIT 1; RECESSIVE TRAIT 2 3 3 1 9:3:3:1
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