1. Nonsteroidal Antiasthma Agents
Chapter 12
RES219
Pharmacology

2. Three groups
Cromolyn-like agents
Antileukotrienes
Monoclonal antibody

3. Cromolyn-like agents AKA mast cell stabilizers
Prevents rupture of the mast cells
Cromolyn Sodium

4. Antileukotriene Agents
Terms:
arachidonic acid
leukotrienes
zileuton (Zyflo)
zafirlukast (Accolate)
montelukast (Singulair)
Blocks production or action of leukotrienes

5. Monoclonal Antibodies
Omalizumab (Xolair)
Blocks IgE from binding to the IgE receptor on the surface of mast cell

6. Antihistamines Histamine stored in tissue mast cell Examples: Claritin
Zyrtec
Benadryl
Allegra