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Discovery of DNA and DNA Structure
Deoxyribonucleic Acid pp
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DNA Stores and transmits genetic information to make proteins
Made up of repeating units of nucleotides
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Griffith’s Experiments
Showed that hereditary material can pass from one cell to another
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Avery’s Experiments Showed that DNA is the hereditary material that transfers information between bacterial cells.
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Hershey-Chase Experiment
Confirmed that DNA, and not protein, is the hereditary material.
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Watson and Crick & Franklin
Determined the shape of DNA to be a double helix
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Location Prokaryotes: floats in cytoplasm
Eukaryotes: wrapped around proteins in the nucleus
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DNA Structure Nucleotides have three parts: Deoxyribose Sugar
Phosphate Group Base
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Complementary Base Pairing
Purine bonds to Pyrimidine A bonds to T G bonds to C
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DNA Bases Purines: Two-ringed bases Pyrimidines: One-ringed Bases
Adenine and Guanine Pyrimidines: One-ringed Bases Thymine and Cytosine
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DNA Bonds Two strands (at the bases) are held together by weak hydrogen bonds. The sugar phosphate backbone is held together by covalent bonds
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Double helix: DNA is double-stranded and coiled like a spiral staircase.
Backbone is like the railing and the bases are the steps.
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