1. Good Morning All of YOU Thanking You for select my research paper for presentation
THANK YOU VERY MUCH
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

2. Dr. S. Pholtan Rajeev BSMS (Hon.)
“Efficacy of Sida cordifolia Linn. decoction as Vehicle of Drug (ANUPANAM) in the management of Joint Disorders” – a clinical study
Dr. S. Pholtan Rajeev
BSMS (Hon.)
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

3. Presenting…… INTRODUCTION OBJECTIVE METHODS & MATERIALS
RESULTS & DISCUSSION
CONCLUSION
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

4. INTRODUCTION
Symptoms of Joint disorders are compared with symptoms of keel vaatham in siddha system of medicine.
It can define as a disease of joint with symptoms of joint pain, joint swelling, limitation and painful movements, restricted joint movement.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

5. INTRODUCTION
Identified problem is treatment of keel vaatham is curing certain period of time (4-5 follow-up medication) by present available Siddha medicines in government institutions.
Identify a new combine poly herbal drug for management of keel vaatham in short time.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

6. INTRODUCTION
In medical science, mainly analgesics, anti-inflammatory drugs or finally surgery are the options for the treatment of Osteoarthritis. Considering all these factors, the present study was taken up with the objective to evaluate the efficacy of herbal medicine with vehicle (Anupanam) to keel vaatham (osteoarthritis).
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

7. INTRODUCTION
Anupanam is the main roll in administration of drug in Siddha system of medicine. One medicine cure many diseases by changing of Annupanam is special characteristic of poly herbal medicine.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

8. OBJECTIVE To relief the Symptoms of Arthritis through Herbal Medicine.
To identify effectiveness of anupanam.
To asses efficacy of combination of drug and anupanam for joint disorders.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

9. METHODS & METERIALS Type of Research: Research area:
Control Clinical Study
Research area:
District Ayurvedic Hospital (DAH), Mullaitivu, Sri Lanka
Research period: 03 months
Research Samples: 60 patients
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

10. Methodology Literature review
Identify and authenticate the drug materials including in the selected formula.
Making for sample and check the quality for phyto-chemicals and standardization.
Making the final product of the research drug.  
Clinical test for the drug from 60 patients in OPD (Out Patient Department) and data collecting from a suitable Proforma.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

11. Research drug: Sida cordifolia Linn. SIDDHA SYMPOSIUM - 2014
Dr.S.R.Pholtan Rajeev

12. Research Drug Research drug: Anupanam (vehicle) Ingredients:
Sittamatti - Sida cordifolia Linn. Whole plant
Method of preparation:
Normal Decoction preparation. Add 08 cups of water then heat and reduction for 01 cup for 01 day.
Research drug: Medicine + Anupanam
Anupanam : Sittamatti decoction
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

13. Research drug (from field collection): Sida cordifolia Linn.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

14. Research drug (END PRODUCT): Sida cordifolia Linn.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

15. Methodology Assessment Criteria Final Assessment Criteria:
High Marked. (not cured)
Moderate improvement.
Mild improvement.
Very Mild improvement.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

16. Data Analysis Score initial final Dr.S.R.Pholtan Rajeev 2 3 4 5 6 7 8 9 10
initial
Very Mild
Mild
Moderate
Severe
final
High Marked
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

17. Clinical Trial Grouping the Samples:
In this research, total sample divided into two (02) groups but all are same symptomatically Arthritis condition. Those two groups are given below,
Group I: Arthritis patients with medicine + Sittamatti decoction treatment. (30 patients)
Group II: Arthritis patients with medicine without anupanam treatment
Without any decoction or liquid formulas. (30 patients)
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

18. GROUP-I (Research drug)
Medicine
Dosage
Period of intake
Vehicle (Anupana)
Vathagajendra singhe rasa [4]
02 pills
Twice a day
Sittamatti decoction
Mudakku Chooranam [1]
01g
Thrice a day
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

19. GROUP – II (Control drug)
Medicine
Dosage
Period of intake
Vehicle (Anupana)
Vathagajendra singhe rasa
02 pills
Twice a day -
Mudakku Chooranam
01g
Thrice a day
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

20. RESULTS & DISCUSSION
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

21. No. Sample No. Sex Age Symptom Initial score Final score1 4 M 45
pain in right knee joint 10 3 2 13 55
pain in both knee joint 21 52 28 59
pain and swelling in knee joint
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

22. No. Sample No. Sex Age Symptom Initial score Final score1 4 M 45
pain in right knee joint 10 3 2 6 F 70
pain in left knee joint 8 15 62
tenderness in shoulder 9
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

23. Sample No. Initial score 1st month 2nd month 3rd month Final score 1st9 7 6 5 4 2 8 3 10 11 12 13 14 15
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

24. Final Assessment Dr.S.R.Pholtan Rajeev SIDDHA SYMPOSIUM - 2014 0 1 2 3 2 3 4 5 6 7 8 9 10
initial
Very Mild
Mild
Moderate
Marked
final
High Marked
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

25. Clinical trial process
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

26. Clinical trial process
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

27. CONCLUSION
Final Score is (01, 02)- 43.3% % = 73.3% - High Marked improvement
Final Score is (03, 04, 05) 10% +13.3% % = 26.6% - Moderate improvement
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

28. CONCLUSION
In statistical result says, compare with sample group-I & sample group-II was (p value < 0.05) within three month of treatment. Finally, we concluded effectiveness of our vehicle with medicine most effective than medicine control Group -II for symptoms of joint disorder significantly.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

29. CONCLUSION
Therefore anupanam with medicine (Group-I) is best than medicine without anupanam (Group-II). Vatha Gajendra Singhe Rasa with Sida decoction, Mudakku Chooranam with Sida decoction treatment are better clinically efficacy than Vatha Gajendra Singhe Rasa without Sida decoction, Mudakku Chooranam without Sida decoction treatment.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

30. REFERENCES Text References:
Ramanathan. P, MD(s), ‘Siddha Pharmacopoeia’, All Sri Lankan Siddha Ayurveda Medical Officers’ Union, Sri Lanka, 1st Edition-2000, page No: 102.
Narayanaswami.V, HPIM, ‘Pharmacopoeia of Hospital of Indian Medicine – SIDDHA’, Tamil Nadu Siddha Medical Board, Madras , 2nd Edition-1995, Page No: 29.
Murugesa muthaliyar.K.S, “Gunapadam- Mooligai thokuppu” (1st Part), University of Indian Medicine, Madras , 3nd Edition- 1936, page no:09, 10, 36, 37,383, 384, 385, 386.
Department of Ayurveda, “Ayurveda Pharmacopoeia of Sri Lanka”, Vol-03, 1976, pages: (in Sinhala)
Ponnaiyah.I,“Sekarasa sekara vaiththiyam” Provincial Department of Indigenous Medicine, North-East Province, Sri Lanka, 2000, page no: 115, 116, 217.
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev

31. THIS IS ONLY ONE DROP OF AN OCEAN, TRY TO DO EVERYONE FOR ONE DROP OF AN OCEAN !!!!!!!!!!! THANK YOU
SIDDHA SYMPOSIUM
Dr.S.R.Pholtan Rajeev