1. Diabetes mellitus, amyloidosis of the islets and ulcer
Diabetes mellitus, amyloidosis of the islets and ulcer. A and B, Amyloidosis of the islets. A, The single islet in the center of the image contains a prominent amount of acellular eosinophilic material. B, Apple-green birefringence under polarization (arrow) on Congo red stain confirms that the material in the islet is amyloid. C, Due to loss of sensation secondary to peripheral neuropathy and poor circulation due to vascular damage, diabetics are prone to develop nonhealing ulcers (arrow) of the extremities. A, Hematoxylin and eosin, 400×; B, Congo red, 400×.
Source: Chapter 18. Endocrine Pathology, Pathology: The Big Picture
Citation: Kemp WL, Burns DK, Brown TG. Pathology: The Big Picture; 2008 Available at: Accessed: December 30, 2017
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