1. HW: Transcription and Translation
Pre-AP Biology
Search for the YouTube video “Transcription and Translation”
by Alyssa Dolny.
Complete on Page 27 (use another sheet of paper and attach to I.A.N. later) of your I.A.N. using Cornell Notes. Due Friday.

2. Let’s get some things straight…
Replication- to make an exact copy
Replication is like making a photocopy
Transcription- to transfer from one recording form to another
Transcription is like taking notes (same information, different form)

3. Well…
Copies are good to have as a backup—it’d be bad if something happened to DNA
You can just put down the part of the information you need—shorter/simpler
Think of it like this:
DNA = master copy
RNA = blueprints…you don’t need the blueprints for the whole house to build the foundation

4. Central Dogma We’re only talking about the first part today 
Translation
Transcription
DNA
RNA
Protein
Ribosome
Nucleus

5. Transcription (big ideas)
Is the first step in making a protein (polypeptide)
Occurs in the nucleus
DNA is used to make RNA
RNA is then sent out into the cell to make proteins
It’s usually just a section of the DNA strand (gene) that codes for one specific protein

6. There are three main differences between DNA and RNA: 1) The sugar in RNA is ribose instead of deoxyribose. 2) RNA is single-stranded. 3) RNA contains uracil instead of thymine.

7. Comparing base pairing rules
DNA to DNA
DNA to RNA
C  G
G  C
T  A
A  T
C G G C T  A A U

8. Summarize the DNA to RNA base pairing rules in exactly 8 words.

9. Messenger RNA (mRNA) carries copies of instructions from DNA in the nucleus to the ribosome to make proteins.