1. ELIXIR Safeguarding the results of life science research in Europe
Niclas Jareborg

2. ELIXIR underpins life science research – across academia and industry
ELIXIR connects national bioinformatics centres and EMBL-EBI into a sustainable European infrastructure for biological research data
medicine
agriculture
bioindustries
ELIXIR underpins life science research – across academia and industry
environment

3. A distributed infrastructure to scale with the challenges
ELIXIR infrastructure for Europe’s life science research sector
ELIXIR Nodes build local bioinformatics capacity throughout Europe
ELIXIR Nodes build on national strengths and priorities
Biology has by far the largest research community:
~500,000 life science researchers in Europe
>8 million web hits a day at EBI alone
Creating a robust infrastructure for biological information is a bigger task than any individual organisation or nation can take on alone
These are issues of such complexity that no single institution or country can tackle alone
At the global level interactions with:
RDA
NIH BD2K
GA4GH

4. ELIXIR Infrastructure
Data
Sustain core data resources
Tools
Services & connectors to drive access and exploitation
Compute
Access, Exchange & Compute on sensitive data
Interoperability
Integration and interoperability of data and services through standards.
Training
Professional skills for managing and exploiting data
5 platforms

5. ELIXIR-EXCELERATE

6. ELIXIR-
ELIXIR prioritised by ESFRI in for implementation and operation support:
€19 million 4 year project, 41 partners in 15 countries
starts September 2015
Accelerate the implementation of ELIXIR across Nodes
Develop and connect resources and services (from Nodes)
Build bioinformatics capacity across Europe
Five platforms: Data; Tools; Compute; Interoperability; Training
Four Use Cases: Rare diseases; Human data; Plant genotype- phenotype; Marine metagenomics

7. EXCELERATE consortium
41 partners
15 countries

8. EXCELLERATE Structure

9. Resource management and governance principles of data and tools
Data integration through a federated approach
Scalable access and analysis of research data
Role of communities developing around research data, computing and tools
Actions to develop a culture of sharing and participation

10. EXCELERATE
The success of ELIXIR service implementation is measured by and dependent on the advances reached in the scientific use cases and training.
Use existing European e-Infrastructure resources to support the implementation of use cases and training.
E.g. EGI federated cloud
A particular challenge how to enable access, processing and transfer of human data.
Working with Global Alliance for Genomics and Health (GA4GH)
Framework for Responsible Sharing of Genomic and Health-Related Data

11. Thank you! Questions? Comments?

12. Human genomics data management

13. ELIXIR pilot with EGA archive6. 2.
EGA portal
EGA dataset metadata 1.
eduGAIN 3. SP
REMS 5. SP 4.
EGA Dataset delivery
EGA datasets
In the EGA AAI pilot
REMS integrated to EGA service of EBI
REMS creates workflows based on EGA metadata
Next extending to new EGA Data access committees
In the GEANT Enabling Users pilot, REMS and EGA login
integrated to eduGAIN
opened for R&E feds in CH, FI, IE, DE, IT, NL, FR
Also studied EGA LoA requirements

14. ELIXIR AAI design (draft)
Relying services
EGA
wiki … … …
Cloud
Intranet
Data archive
ELIXIR AAI
Dataset authorisation management
Credential translation
ELIXIR Directory
Group/role management
ELIXIR Proxy IdP
Bona fide management
Attribute self-management
External authentication (e-infrastructures)
eduGAIN IdPs
Common IdPs

15. ELIXIR identity Each user has one ELIXIR identity
e.g.
ELIXIR Proxy maps external authentication providers to it
e.g. (eduGAIN)
e.g. (Google)
e.g (ORCID)
Also local username/password possible
Relying services
EGA
wiki … … …
Cloud
Intranet
Data archive
ELIXIR AAI
Dataset authorisation management
Credential translation
ELIXIR Directory
Group/role management
ELIXIR Proxy IdP
Bona fide management
Attribute self-management
External authentication (e-infrastructures)
eduGAIN IdPs
Common IdPs

16. ELIXIR identity Relying services ELIXIR AAI
EGA
wiki … … …
Cloud
Intranet
Data archive
ELIXIR AAI
(ELIXIR ID)
External authentication (e-infrastructures)
(eduGAIN)
(Google ID)
(ORCID)

17. REMS – Resource Entitlement Management System
Principal investigator Applicant
Research group Members of the application
Metadata on dataset 1&2
Dataset 1
Dataset 2
DAC 1 Approver
DAC 2 Approver
REMS
Workflow
Reports
Entitlements
IdP SP
1. Apply for access
4. Approve
5. Access
3. Circulate to approver
2. Commit to licence terms
Software
Federated authorisation
Developed by ELIXIR-FI
Open source available (LGPL)
Deployment
Life sciences: EGA (ELIXIR), biobanks
Linguistics (CLARIN-FI)
Social science (CESSDA-FI)
Other national Finnish services