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A and B. Ghrelin secretion after bariatric surgery
A and B. Ghrelin secretion after bariatric surgery. Some investigators have suggested that ghrelin secretion is dramatically decreased after gastric bypass. Other groups have shown statistically insignificant changes in ghrelin levels after gastric bypass, (RYGBP) but significant decreases after sleeve gastrectomy (SG). A: green = gastric bypass; blue = obese controls; red = normal weight controls; B: blue = fasting; pink = postprandial. B. Top = RYGBP; B bottom = SG. (Fig A reproduced with permission from Cummings DE, et al: Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med 346:1623, Copyright ©2002 Massachusetts Medical Society. All rights reserved. Fig B reproduced with permission from Karamanakos SN, et al: Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: A prospective, double blind study. Ann Surg 247:401, 2008.) Source: Stomach, Schwartz's Principles of Surgery, 10e Citation: Brunicardi F, Andersen DK, Billiar TR, Dunn DL, Hunter JG, Matthews JB, Pollock RE. Schwartz's Principles of Surgery, 10e; 2014 Available at: Accessed: December 31, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
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