2. THE HUMAN BRAIN ~85 billion neurons Million-billion synapses
3.2 million km of wiring
Caenorhabditis elegans
Brain does not replicate the outside world.
It abstracts and restructures external reality.
Mental processes interpret sensory inputs, plan & execute response for attributes like attention, memory, percepts and concepts.
THE HUMAN BRAIN

3. Understanding the Nervous System:
Molecules
Understanding the Nervous System:
A Multi-faceted Approach
from Molecules to Behaviour
Behaviour
Neurons
Networks
Systems

4. STRUCTURE OF CNS
Established as a multi-disciplinary centre in 2009 with core
faculty, associate & adjunct faculty from other departments
with interest in neuroscience
Prof. V. Ravindranath
Founder Chairperson

5. What we do at the CENTRE FOR NEUROSCIENCE
GENETICS
BEHAVIOR
MOLECULAR
BIOLOGY
NETWORK
ELECTROPHYSIOLOGY
COMPUTATION

6. STRUCTURE OF CNS Primary Faculty Prof. Aditya Murthy
Prof. Viji Ravindranath
Prof. Naren Ramanan
Prof. Arun Sripati
Prof. Supratim Ray
Dr. Balaji Jayaprakash
Dr. Deepak Nair
Dr. Sridharan Devarajan
Faculty Fellows
Dr. Sachin Deshmukh
Dr. Reddy K.
Dr. Mini Jose Deepak
Dr. Swanand Marathe
Associate Faculty
Prof. Veni Madhavan (CSA)
Prof. G. Rangarajan (Maths)
Prof. P. Seshagiri (MRDG)
Prof. Chandra Sekhar Seelamantula (EE)
Adjunct Faculty
Prof. A. Sinha (NIAS)
Prof. S. Vishwamitra (Ramaiah & Shri
Sathya Sai Institute)

7. Structure and Synaptic Organization
How do neurons develop their structure?
MINI JOSE DEEPAK
CNS Development,
Structure and Synaptic
Organization
Astrocyte development in mammalian CNS
NAREN RAMANAN
Neuronal receptor biology
REDDY KOMMADDI
How does molecular organization and regulation contribute to synaptic function?
DEEPAK NAIR

8. Neurobiology of Learning and memory, Behaviour and Disease
How are memories stored in neural networks?
BALAJI JAYAPRAKASH
Why do neurons degenerate & lose connections leading to memory loss in Alzheimer’s disease?
V. RAVINDRANATH
Role of astrocytes in behaviour and disease
SWANAND MARATHE

9. Neurobiology of Motor Control, Attention,
Visual Processing and Spatial Navigation
How do we pay attention?
SUPRATIM RAY
SRIDHAR DEVARAJAN
How do we plan and control our actions?
ADITYA MURTHY
How do we recognize objects?
SP ARUN
How do we navigate?
SACHIN DESHMUKH

10. Center for Neuroscience (2009-14)
Faculty 8
Faculty Fellows 4
Associate Faculty
Adjunct Faculty 2
Post Doctoral Researchers 5
Students
Current: 37 Awarded: 6 Joint: 13
Project Staff 34
Office Staff (Institute) 3
Total
116

11. Funding Source
( )
Numbers
DBT-Wellcome Trust Grants 4
DBT/DST Grant 16
Swarna Jayanti 1
Ramalingaswami/Ramanujam
IYBA
JC BOSE FELLOWSHIP
MCGU Grant
UGC Grant
IFCPAR
Tata Grant on AD

12. Alzheimer’s Disease: Understanding mechanisms for early diagnosis and treatment
Project funded by Tata Trust
To understand the pathophysiological changes occurring early in life that lead to onset of Alzheimer’s disease (AD) during aging at several levels of organization from molecular to behavioural and structural changes in the brain.
This study brings together expertise in molecular and cellular biology, electrophysiology, imaging, behavioural, clinical disciplines and mathematical modeling.