1. Wednesday, 22 September Ch 11 Endocrine System
Seminar: Thursday, 11 am Olin Theater. Diabetes, Stress, & Depression!
The Hypothalamus and Pituitary Glands
Unique anatomy
Long & short loop negative feedback
Some examples of endocrine disorders
Stress and cortisol

2. 1QQ # 7
Give the definition of “hormone” and explain why, according to this definition, renin isn’t actually a hormone.
What’s different about the cells of the zona glomerulosa in the adrenal cortex that allows them to secrete aldosterone but not glucocorticoids?
Where does Angiotensin II come from and what does it do?
Why do steroid hormones and thyroid hormones remain in the bloodstream much longer than peptide hormones and catecholamine hormones?

3. Thyroid Gland TH =T3 and T4 S1 Fenestrated Capillary
(typical of endocrine glands)

4. S2
Synthesis, Storage and Secretion of T3 and T4 Roles of TSH (Thyroid Stimulating Hormone)
Tropic: directs (controls)
Trophic: growth
TH increases cell metabolism & heat production (BMR)

5. Fig. 11.12a S3 Receives input from many regions of brain; many factors
Affect its function
Homeostatsis center.
11.12a.jpg

6. 6 Fig. 11.12b S4 Neurohypophysis Adenohypophysis
11.12b.jpg 6
Vasopressin (= Antidiuretic hormone) Oxytocin

7. Typical Blood Flow Portal System
Artery – arteriole- capillary –venule- vein –heart
Portal System
Artery – arteriole- capillary –portal vessel –capillary –venule- vein –heart
Hepatic portal system
Hypothalamo-hypophyseal portal system
Vasculature of nephrons

8. Release-inhibiting Hormone
Tropic hormones control the function
Trophic hormones promote survival and growth of targets
S 6 A S P
Hypothalamo-hypophyseal portal system
11.17.jpg
Releasing Hormone
Release-inhibiting Hormone

9. Long-loop negative feedback
Tropic hormones control the function
Trophic hormones promote survival and growth of targets
S 7
Releasing Hormone
Release Inhibiting Hormone
Short-loop Neg. Feed.
Long-loop negative feedback
11.17.jpg