1. Suraneni et al, table S7: Representative genes commonly upregulated in young transgenic (fl26y and svb9y) and old wt (wto) VPs compared to young wt (wty) VPs
wto(vs)wty fl26y(vs)wty svb9y(vs)wty
in wto: 200 genes ≥2 fold in fl26y: 200 genes ≥1.7 fold; in svb9y: only 51 genes ≥1.5 fold
Gene Fold Gene Fold Gene Fold
Ski (Sloan-Kettering viral oncogene) Ski 12.4
Ang 3 (angiogenin 3) Ang
Ang , 5.1 Ang , 2.6
Ang Ang
Ang Ang
Angptl4 (angiopoietin-like 4) Angptl4 1.7
Agtrap (angiotensin II, type I Agtr ,1.3
receptor associated protein) (angiotensin receptor 1)
Usp30 (ubiquitin-specific protease 30) Usp
Aldh8a1 (aldehyde dehydrogenase Aldh8a Aldh8a
8 family, member A1)
Gab3 (growth factor receptor bound Gab3 7.2
protein 2-associated protein 3)
Gnao1 (GTP-binding protein Gnao
alpha subunit)
Pik3c2g (PI3K, C2 domain Pik3c2g
containing,  polypeptide)
Plxna1 (Plexin A1) Plxna Plxna
Saa2 (serum amyloid A 2) , 2.0 Saa2 2.9, Saa , 1.5
Saa Saa Saa
Psca (prostate stem cell antigen) Psca 3.2
Slc25a Slc25a17 2.1, 1.7
Slc4a Slc4a1 4.4
Cxcl14 (chemokine ligand 14) Cxcl
Rkhd1 (ring finger (C3HC4 type) Rkhd Rkhd1 1.7
and KH domain containing 1)
Fxyd4 (FXYD domain-containing ion Fxyd 3.8
transport regulator 4)
Eif4e (eukaryotic translation Eif4el3 2.0
initiation factor 4E)
Igfbp Igfbp6 1.3
Shown are some representative genes COMMONLY upregulated in wto and/or fl26y and/or svb9y compared to wty VPs. Gene names and fold increase are
indicated. Some genes showed upregulation on several probesets. Genes marked in red are commonly upregulated in all 3 sets of comparisons.