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Volume 380, Issue 9836, Pages 44-49 (July 2012)
Magnesium for aneurysmal subarachnoid haemorrhage (MASH-2): a randomised placebo-controlled trial Sanne M Dorhout Mees, MD, Prof Ale Algra, MD, Prof W Peter Vandertop, MD, Fop van Kooten, MD, Hans AJM Kuijsten, MD, Jelis Boiten, MD, Prof Robert J van Oostenbrugge, MD, Rustam Al-Shahi Salman, PhD, Pablo M Lavados, MD, Prof Gabriel JE Rinkel, MD, Walter M van den Bergh, MD The Lancet Volume 380, Issue 9836, Pages (July 2012) DOI: /S (12) Copyright © 2012 Elsevier Ltd Terms and Conditions
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Figure 1 Trial profile The Lancet , 44-49DOI: ( /S (12) ) Copyright © 2012 Elsevier Ltd Terms and Conditions
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Figure 2 Distributions of mRS score in the magnesium and placebo groups Data are number of patients with each mRS score. Tested with Mann-Whitney U test; p=0·95. mRS=modified Rankin Scale score. The Lancet , 44-49DOI: ( /S (12) ) Copyright © 2012 Elsevier Ltd Terms and Conditions
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Figure 3 Subgroup analyses for primary outcome
WFNS score was unknown for one patient. Treatment type was unknown for two patients. RR=risk ratio. WFNS=World Federation of Neurological Surgeons.12 The Lancet , 44-49DOI: ( /S (12) ) Copyright © 2012 Elsevier Ltd Terms and Conditions
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Figure 4 Meta-analysis of effect of magnesium therapy after subarachnoid haemorrhage on poor outcome The Lancet , 44-49DOI: ( /S (12) ) Copyright © 2012 Elsevier Ltd Terms and Conditions
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