1. Tuesday, Jan. 12 A Day Wednesday 8AM sharp meet in Stuber Gym
Sharpened Pencils, ID & Calculator
ACT Science Advice
Questions over experiments?
Quiz: DNA Structure
Notes- History of DNA

2. Discovery of DNA
A Brief History

3. Friedrich Meisher 1871 Used old wound wrappings to take pus samples
From the samples, he isolated and extracted DNA
Experiment documented gone unnoticed for many years

4. Phoebus Levene 1910 Determined that DNA contains 3 parts:
nitrogenous bases (adenine, thymine, guanine and cytosine)
Phosphate
Deoxyribose Sugar

5. Erwin Chargaff 1949
Virus pieX174- single stranded DNA molecule

6. Erwin Chargaff 1949
Determined that the amounts of A=T and the amounts of G=C
Discovered complementary base pairing
Did not respect Watson and Crick as scientists

7. Rosalind Franklin 1950s
X- ray diffraction to determine double helix structure of DNA
Calculated the dimensions of a DNA molecule

8. Maurice Wilkins Worked with Rosalind Franklin
Showed Francis Crick and James Watson the x- ray diffraction of DNA
DID NOT GAIN PERMISSION from Franklin

9. Watson and Crick 1953
Used information from Levene, Chargaff and Franklin (among others)
Built a model of the structure of DNA
Wrote a paper regarding their findings
Made hypothesis for DNA replication

10. Protein (Histones)