1. Botulinum Toxin Reduces Dysphagia in Patients With Nonachalasia Primary Esophageal Motility Disorders 
Tim Vanuytsel, Raf Bisschops, Ricard Farré, Ans Pauwels, Lieselot Holvoet, Joris Arts, Philip Caenepeel, Dominiek De Wulf, Kostas Mimidis, Nathalie Rommel, Jan Tack 
Clinical Gastroenterology and Hepatology 
Volume 11, Issue 9, Pages e2 (September 2013)
DOI: /j.cgh
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2. Figure 1
The effect of BTX or sham injection on the (A) total symptom score and the (B) total dysphagia score. The numbers next to the connecting line indicate the number of subjects if several patients had the same evolution of the symptom score.
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3. Figure 2
Long-term prognosis after BTX injection in (A and C) group 1 (BTX first) (white bars) and (B and D) group 2 (sham first) (shaded bars). *P < .05; **P < .01.
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4. Figure 3
Total symptom score, total dysphagia score, and symptom scores for dysphagia for solids and liquids and chest pain at 1 month after treatment with BTX (white bar) or sham injection (shaded bar).
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5. Figure 4
Responder rates, defined by a modification of the Vantrappen criteria for achalasia, in group 1 (BTX first; solid line) and group 2 (sham first; dashed line).
Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh )
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6. Figure 5
Manometry before and after BTX injection. (A and B) Maximal distal amplitude in (A) group 1 (white bars; BTX first) and (B) group 2 (shaded bars; sham injection first). (C and D) Representative pictures of a patient with jackhammer esophagus (C) before and (D) 1 month after BTX.
Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh )
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7. Supplementary Figure 1 CONSORT flow diagram.
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8. Supplementary Figure 2
Weight changes 1 month after BTX (white bar) and sham injection (shaded bar).
Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh )
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9. Supplementary Figure 3
Long-term prognosis after BTX injection in patients with manometry-confirmed distal esophageal spasm in (A and C) group 1 (BTX as the first treatment; n = 7; white bars) and (B and D) group 2 (sham as the first treatment; n = 8; shaded bars). *P < .05; **P < .01, Friedman test with Dunn correction for multiple testing.
Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh )
Copyright © 2013 AGA Institute Terms and Conditions