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Fig. 3 Summary estimates of the relative risks for the different surgical techniques for late mortality. Comparing the two main techniques, EVR showed.

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Presentation on theme: "Fig. 3 Summary estimates of the relative risks for the different surgical techniques for late mortality. Comparing the two main techniques, EVR showed."— Presentation transcript:

1 Fig. 3 Summary estimates of the relative risks for the different surgical techniques for late mortality. Comparing the two main techniques, EVR showed a significantly reduced risk on late mortality (RR = 0.67, p < 0.001) compared to the linear repair (RR = 1.83, p < 0.001). LVRS: LV reconstruction surgery; Circular: direct reconstruction of LV wall using a circular patch; EVR: endoventricular reconstruction of the LV with or without a patch; linear: linear repair; linear with septoplasty: linear repair with a plasty of the interventricular septum; septo-exclusion: septo-exclusion technique. From: Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease Eur J Cardiothorac Surg. 2008;34(6): doi: /j.ejcts Eur J Cardiothorac Surg | © 2008 European Association for Cardio-Thoracic Surgery

2 Table 1 Causes of early mortality after LVRS (20 studies, n = 3729 patients).
From: Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease Eur J Cardiothorac Surg. 2008;34(6): doi: /j.ejcts Eur J Cardiothorac Surg | © 2008 European Association for Cardio-Thoracic Surgery

3 Table 2 Causes of late mortality after LVRS (13 studies, n = 2702 patients).
From: Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease Eur J Cardiothorac Surg. 2008;34(6): doi: /j.ejcts Eur J Cardiothorac Surg | © 2008 European Association for Cardio-Thoracic Surgery

4 Fig. 4 Comparison of left ventricular reconstruction surgery with concomitant CABG or mitral valve surgery on early (inhospital or 30-day mortality) and late (5-year) mortality. Concomitant CABG was not associated with an increased risk for early mortality (RR = 1.018, p = 0.858), but was associated with a significantly lower risk for late mortality (RR = 0.28, p < 0001). Concomitant mitral valve surgery was associated with both an increased risk for early (RR = 1.57, p = 0.001) and late mortality (RR = 4.28, p < 0.001). MVR: mitral valve surgery (repair or replacement); CABG: coronary artery bypass grafting. From: Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease Eur J Cardiothorac Surg. 2008;34(6): doi: /j.ejcts Eur J Cardiothorac Surg | © 2008 European Association for Cardio-Thoracic Surgery

5 Fig. 5 Early (inhospital or 30-day mortality) and late (3-year) mortality in patients with heart failure. The pooled, median and average weighted early mortality (14 studies, n = 4135 patients) were 5.2%, 12.9% and 11.6%, respectively. The pooled, median and average weighted late mortality (10 studies, n = 802 patients) were 15.7%, 14.7% and 15.7%, respectively. From: Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease Eur J Cardiothorac Surg. 2008;34(6): doi: /j.ejcts Eur J Cardiothorac Surg | © 2008 European Association for Cardio-Thoracic Surgery

6 Fig. 6 Summary estimates of the relative risk for EVR (8 studies, n = 2376 patients) versus linear repair technique (4 studies, n = 1045 patients) in patients with heart failure. EVR shows a significantly reduced risk for early mortality (RR = 0.66, p = 0.004). EVR: endoventricular reconstruction of the LV with or without a patch; linear: linear repair. From: Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease Eur J Cardiothorac Surg. 2008;34(6): doi: /j.ejcts Eur J Cardiothorac Surg | © 2008 European Association for Cardio-Thoracic Surgery

7 Fig. 2 Summary estimates of the relative risks for the different surgical techniques for early mortality. Comparing the two main techniques, EVR showed a reduced risk for early mortality (RR = 0.79, p = 0.002) compared to the linear repair (RR = 1.38, p < 0.001). LVRS: LV reconstruction surgery; Circular: direct reconstruction of LV wall using a circular patch; EVR: endoventricular reconstruction of the LV with or without a patch; linear: linear repair; linear with septoplasty: linear repair with a plasty of the interventricular septum; septo-exclusion: septo-exclusion technique. From: Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease Eur J Cardiothorac Surg. 2008;34(6): doi: /j.ejcts Eur J Cardiothorac Surg | © 2008 European Association for Cardio-Thoracic Surgery

8 Fig. 1 Cumulative survival after LV reconstruction surgery calculated from 62 published reports (n = 12,331 patients) that reported on early mortality and 47 published reports following 8571 patients for a median of 49 months (25th, 75th percentile = 23, 62 months). Cumulative 1-, 5- and 10-year survival were 88.5%, 71.5% and 53.9%, respectively. Straight line: weighted average cumulative survival; dotted lines: 95% confidence intervals. From: Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease Eur J Cardiothorac Surg. 2008;34(6): doi: /j.ejcts Eur J Cardiothorac Surg | © 2008 European Association for Cardio-Thoracic Surgery

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