1. Edward Jenner
Caden and Meredith!!!!

2. SMALLPOX
-10,000 B.C
-Introduced to Americas by Spanish conquistadors and African slaves
-Smallpox survivors became immune
-Nursed the sick
-Inoculation: matter from smallpox pustule used to infect someone not yet immune
-Often led to spread of other diseases

3. Symptoms of Smallpox
-rash that develops into abscesses filled with liquid
-chills
-severe back pain
-abdominal pain
-vomiting
-high fever

4. Jenner’s EARLY LIFE
-Born 1749 Berkeley, orphaned at age 5, lived with brother
-1764 surgeon George Harkwicke apprenticeship
-Surgeon John Hunter in London at 21
-Studied natural science for 2 years
-Returned to Berkeley to study medicine

5. SEARCH FOR CURE
-Became interested in cowpox during Harwicke apprenticeship
-Saw milkmaids rarely caught smallpox, but almost always caught cowpox
-Disease found most commonly in milkmaids as it is transferred between
species
-Hypothesized could intentionally infect people with cowpox to protect them

6. EXPERIMENT
-Used matter from a milkmaid’s cowpox lesions to immunize a young boy
-Nine day fever, but soon felt much better
-Infected with matter from a smallpox lesion a few months later, no signs of illness
-Concluded he was correct, smallpox could be protected against by being infected
by cowpox
-Titled cure “vaccination” after latin word for cowpox

7. SPREAD OF VACCINATION -Initially rejected by Royal Society 1797
-Published findings, met with mixed reviews
-Practice eventually adopted by various surgeons
in 1799, others followed until vaccination
was accepted across the world

8. EFFECTS OF VACCINATION
-Safer and more reliable than traditional inoculation
-Despite initial rejection, vaccination soon became widely used, saving many lives
-Eventually became compulsory in several countries
-Future scientists modeled vaccines for numerous other diseases after Jenning’s
-15 vaccinations before age 18 now

10. BIBLIOGRAPHY
Riedel, Stefan. “Edward Jenner and the History of Smallpox and Vaccination.”
Proceedings (Baylor University. Medical Center), Baylor Health Care System, Jan.
2005,
“Science Museum. Brought to Life: Exploring the History of Medicine.” Edward Jenner
( ), Science Museum,

11. BIBLIOGRAPHY
“Jenner Tests Smallpox Vaccine.” History.com, A&E Television Networks, 5ADAD,
“Edward Jenner and the Development of the First Modern Vaccine.” VBI Vaccines
Inc., EVLP Platform, 22 Dec. 2015,