1. Structure of red cell glycophorins. A
Structure of red cell glycophorins. A. Organization of glycophorin (GP) A, the major red cell sialoglycoprotein. The external domain has 15 tetrasaccharides attached to serine or threonine residues and one complex oligosaccharide attached to asparagine 26. Residues 1 and 5 are Ser and Gly in blood group M red cells and Leu and Glu in blood group N cells. B. Schematic representation of the exons (E1–E6) that contribute to GPA, GPB, and GPE. Each box represents the portion of each protein encoded by a specific exon or insertion sequence. C. Exons that contribute to GPC and GPD. (Adapted from Lux and Palek.4 Used by permission.)
Source: Hereditary Spherocytosis and Hereditary Elliptocytosis, The Online Metabolic and Molecular Bases of Inherited Disease
Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: January 23, 2018
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