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Mendel and the Gene Idea
Laws of Genetics
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Theory of Heredity Before Mendel, people thought offspring were a blend of traits Tall x short = medium Mendel’s experiments did not support this theory Mendel’s work led him to the understanding that traits are carried in pairs (one from each parent)
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Mendel’s 4 hypotheses Hypotheses 1
For each inherited character, an individual has two copies of each gene One on each chromosome Alternative versions of genes account for variations in inherited characters. Alleles are different versions of genes that impart the same characteristic.
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Mendel’s 4 hypotheses Hypotheses 2
Offspring inherit 2 alleles, 1 from each parent for each characteristic (i.e. height, color, etc.) Gametes (sperm or egg) carry only one allele as a result of pair separation during meiosis
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Mendel’s 4 hypotheses Hypotheses 3 The Rule of Dominance
If the two alleles differ one, the dominant allele, is fully expressed in the organism's appearance the other, the recessive allele, has no noticeable effect on the organism's appearance.
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Mendel’s 4 hypotheses Hypotheses 4
The two genes for each character segregate during gamete production. The chromosome count is changed from the diploid number to the haploid number. The genes are sorted into separate gametes, ensuring variation. This sorting process depends on genetic recombination
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mendel’s First law of heredity
Law of Random Segregation A parent randomly passes only one allele for each trait to each offspring
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Mendel’s second law of heredity
Law of Independent Assortment Different gene pairs assort independently in gamete formation. This Law is only true for genes on separate chromosomes!
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Law of independent assortment
P GENERATION -True Breeding Parent Plants All purple (PP) All white (pp) Gametes will be either P or p FIRST FILIAL GENERATION F1 F1 are all purple because of dominance (Pp) SECOND FILIAL GENERATION F2 F2 results in a mathematically predictable 3:1 ratio
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Mendelian Inheritance
Mendelian inheritance patterns Involve genes directly influencing traits Obey Mendel’s laws Law of segregation Law of independent assortment Include Dominant / recessive relationships Gene interactions Phenotype-influencing roles of sex and environment Most genes of eukaryotes follow a Mendelian inheritance pattern
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Predicting Inheritance
Mendel’s Principle of Dominance Some genes (alleles) are dominant and others are recessive. The phenotype (trait) of a dominant gene will be seen when it is paired with a recessive gene. The phenotype of the recessive gene will be “hidden” (not exhibited)
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