1. Jump Start Answer the following in your journal:
What is causing the DNA strands to separate?
Is label A pointing to the original DNA strand or the new one forming?
Is label B pointing to the original DNA strand or the new one forming? B A

2. Review

3. RNA

4. RNA RNA =_____________________ Structural units = nucleotides
Nucleotide – 3 part:
A sugar – ribose
A phosphate group
A ________________ base

5. RNA ______________ Bases – name source for the nucleotides A = adenine
C = cytosine
G = guanine

6. RNA Types
3 types of RNA:
Messenger RNA (mRNA) – ________ genetic information ______ DNA in nucleus to ________; three base sequence called a _________
Ribosomal RNA (rRNA)- makes up __________, where protein is made
Transfer RNA (tRNA)- transfers amino acids from the cytoplasm to the ribosome; its three base sequence is called an anitcodon

7. Differences between… DNA & RNA
Deoxyribose Sugar
2 strands
____________
Remains in nucleus
Ribose Sugar
1 strand
__________
_________ leave nucelus

8. Transcription

9. Transcription
DNA  mRNA (occurs in the _________)
a. The complementary strand of RNA is built by the enzyme ____ ___________
RNA polymerase binds to & separates the DNA strands at promoter sites
Promoter - 3 base sequence that serves as a starting and ending points for RNA to be made

10. Transcription
RNA polymerase uses one _______ of DNA as a ____________ to _______ the complementary strand of mRNA

11. DNA contains…
__________ – nucleotide sequences that do ________ code for proteins
_________ – nucleotide sequences that do code for ___________

12. RNA polymerase copies both introns and exons, but before mRNA leaves the nucleus…
Introns are cut out of the sequence
Exons are spliced (glued) back together to form the final mRNA

13. mRNA travels to the ribosomes (outside of nucleus)