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Specific matrix metalloproteinase 9 (MMP-9) haplotype affect the circulating MMP-9 levels in women with migraine  Alisson Martins-Oliveira, Flavia M.

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Presentation on theme: "Specific matrix metalloproteinase 9 (MMP-9) haplotype affect the circulating MMP-9 levels in women with migraine  Alisson Martins-Oliveira, Flavia M."— Presentation transcript:

1 Specific matrix metalloproteinase 9 (MMP-9) haplotype affect the circulating MMP-9 levels in women with migraine  Alisson Martins-Oliveira, Flavia M. Gonçalves, Jose G. Speciali, Vanessa Fontana, Tatiane C. Izidoro-Toledo, Vanessa A. Belo, Fabiola Dach, Jose E. Tanus-Santos  Journal of Neuroimmunology  Volume 252, Issue 1, Pages (November 2012) DOI: /j.jneuroim Copyright © 2012 Elsevier B.V. Terms and Conditions

2 Fig. 1 Effects of MMP-9 haplotypes on plasma MMP-9 concentrations in the control (Panel A), migraine (Panel B), migraine without aura (MWA; Panel C) and migraine with aura (MA; Panel D) groups. The box and whisker plots show range and quartiles. The boxes extend from the 25th percentile to the 75th percentile, with a line at the median. The whiskers show the highest and the lowest values. #p<0.05 for H4 vs. H3 (panel A). *p<0.05 for H6 vs. H1, H2, H3 (panel B). Journal of Neuroimmunology  , 89-94DOI: ( /j.jneuroim ) Copyright © 2012 Elsevier B.V. Terms and Conditions

3 Fig. 2 Effects of MMP-9 haplotypes on plasma TIMP-1 CONCENTRATIONS in the control (Panel A), migraine (Panel B), migraine without aura (MWA; Panel C) and Migraine with aura (MA; Panel D) groups. The box and whisker plots show range and quartiles. The boxes extend from the 25th percentile to the 75th percentile, with a line at the median. The whiskers show the highest and the lowest values. Journal of Neuroimmunology  , 89-94DOI: ( /j.jneuroim ) Copyright © 2012 Elsevier B.V. Terms and Conditions

4 Fig. 3 Effects of MMP-9 haplotypes on MMP-9/TIMP-1 ratio in the control (Panel A), migraine (Panel B), migraine without aura (MWA; Panel C) and migraine with aura (MA; Panel D) groups. The box and whisker plots show range and quartiles. The boxes extend from the 25th percentile to the 75th percentile, with a line at the median. The whiskers show the highest and the lowest values. Journal of Neuroimmunology  , 89-94DOI: ( /j.jneuroim ) Copyright © 2012 Elsevier B.V. Terms and Conditions

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