1. Mortality Related to Periprocedural MI in CTO-PCI
Patient from a chronic total occlusion (CTO) registry was retrospectively reviewed to determine the prognosis for patients with periprocedural myocardial injury (PMI) following CTO percutaneous coronary intervention (PCI). 1
Primary endpoint: mortality during follow-up period of 4.4 years.
PMI was defined as creatine kinase-myocardial band (CK- MB) >3 times the upper reference limit (URL).
A CK-MB elevation of >3 times and >5 times the URL in 173 failed CTO-PCI patients were 15.6% and 14.5%, respectively.
CK-MB levels >10 the URL was associated with a significant trend toward higher all-cause mortality.
The incidence of PMI was consistently associated with mortality in this patient population.
Mortality occurred in 8.4% (n=89) of patients during follow- up, 5.6% (n=59) of which were caused by a cardiac-related issue.
Conclusion: PMI is associated with increased long-term mortality risk in patients undergoing CTO-PCI.
NPS
Lee SW et al. JACC Cardiovasc Interv. 2016;9(21):