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Volume 147, Issue 1, Pages (November 1999)

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Presentation on theme: "Volume 147, Issue 1, Pages (November 1999)"— Presentation transcript:

1 Volume 147, Issue 1, Pages 115-122 (November 1999)
Autoantibodies against oxidized LDL and endothelium-dependent vasodilation in insulin- dependent diabetes mellitus  Sari Mäkimattila, Jukka S Luoma, Seppo Ylä-Herttuala, Robert Bergholm, Tapio Utriainen, Antti Virkamäki, Matti Mäntysaari, Paula Summanen, Hannele Yki-Järvinen  Atherosclerosis  Volume 147, Issue 1, Pages (November 1999) DOI: /S (99)00180-X

2 Fig. 1 Individual concentrations of circulating autoantibodies against native LDL, oxidized LDL and the ratio of autoantibodies against oxidized versus native LDL (oxLDLab) in normal subjects (CONT, n=33) and patients with IDDM (n=38). Atherosclerosis  , DOI: ( /S (99)00180-X)

3 Fig. 2 Mean±S.E.M. forearm blood flows in the experimental (–) and control (- -) forearm in normal subjects (CONT, n=33), and IDDM patients in good (GOOD, n=11) and poor (POOR, n=12) glycemic control. SNP was infused at rates of 3 (12–18 min) and 10 μg/min (18–24 min), ACh at rates of 7.5 (42–48 min) and 15 μg/min (48–54 min), and l-NMMA at rate of 4 μmol/min for 72–78 min. **P<0.01 for IDDM patients in POOR versus CONT. +P<0.05 for POOR versus GOOD. Atherosclerosis  , DOI: ( /S (99)00180-X)


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