1. Progressive airflow limitation is a feature of children with severe asthma 
Anne M. Fitzpatrick, PhD, MSCR, W. Gerald Teague, MD 
Journal of Allergy and Clinical Immunology 
Volume 127, Issue 1, Pages (January 2011)
DOI: /j.jaci
Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Calculated change per year in prebronchodilator and postbronchodilator FEV1 (shown in liters; A and B), FVC (shown in liters; B and C), and FEV1/FVC ratio (shown as percent predicted; E and F). Lines represent the mean. MMA, Mild-to-moderate asthma; SA, severe asthma. ∗P < .05 and ∗∗P ≤ .01.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
Calculated yearly change in postbronchodilator FEV1 percent predicted values in children with mild-to-moderate and severe asthma. Lines represent the mean. ∗P < .05.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions