1. Optimal Management of Spinal Muscular Atrophy

2. Introduction

3. SMA Is a Genetic Disorder

4. SMA Is a Neuromuscular Disorder

5. SMA Types

6. SMA Type 1

7. SMA Type 2

8. SMA Type 3

9. SMA Type 4

10. SMA Pathophysiology

11. Clinical Course of SMA

12. Genetics of SMA

13. Digenic Process

15. Investigational and Approved Strategies in the Treatment of SMA

16. Clinical Course of SMA

17. Accumulated Complications of Weakness Key Respiratory Problems

18. Treating Respiratory Problems in SMA

19. Additional Factors Affecting Respiration

20. Respiratory Problems in SMA

21. Accumulated Complications of Weakness Key Orthopedic Problems

22. Addressing Orthopedic and Mobility Issues in SMA

23. Accumulated Complications of Weakness Key Nutrition Problems

24. Nutrition Feeding and Swallowing Difficulties

25. Living With SMA

26. Psychosocial Impact of SMA

27. Outcome Measures for Trials and Therapeutic Evaluation

28. SMA Pharmacologic Treatment Initiation

29. Key Points in SMA Diagnosis and Treatment

30. Abbreviations